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  • Lamium maculatum 'Beacon Silver'
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan. Culpeper, in his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nandina domestica Thunb. Berberidaceae. Heavenly bamboo. Distribution: Asia. It contains cyanogenic glycosides which liberate hydrogen cyanide when damaged. Nothing eats it. Pharmacists have also found a chemical in the sap, called nantenine, which is a potential antidote to poisoning by ecstasy with which it shares the same molecular shape. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Protea cyanoides L. Proteaceae King Protea Distribution
  • Euphorbia milii Des Moul. Euphorbiaceae. Crown of Thorns - so called because of its very spiny stems. Distribution: Madagascar. The latex contains a copper-containing amine oxidase, a lectin, lipase, peroxidase, and a diamine oxidase. In vitro the latex is synergistic with ketoconazole against Candida albicans (thrush). All Euphorbia have a toxic white latex, and in Europe this has been used as a folk remedy to treat warts. It can cause skin allergies and the smoke from burning them is toxic. the genus named for Euphorbus (fl. circa 10 BC – 20 AD), the Greek physician to the Berber King Juba II (c. 50 BC – 23 AD) of Numidia, Euphorbia milii is one of the tropical spurges, with fierce, cactus-like spines, grown as a house plant. The sap of spurges is used in folk medicine for treating warts (not very effective), and, historically, as a purgative - the word spurge being derived from the French word for purgation. The sap (probably dried) was administered inside a fig because it is so corrosive that it would otherwise burn the mouth and oesophagus – a technique used today, rather more subtly, with ‘enteric coated’ medications. The sap contains a potential anti-leukaemic chemical, lasiodoplin, and is also used in drainage ditches to kill the snails which carry the parasitic trematode which causes fasciolaris. It does not kill the fish. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Aeonium undulatum cultivar
  • Punica granatum L. Lythraceae Pomegranate, granatum malum, balustines. Distribution: E. Mediterranean to Himalayas. The Pomegranate is in the centre of the Arms of the Royal College of Physicians, perhaps for its use in cooling, and therefore for fevers. However it was the sour pomegranate that would have been used as Dioscorides says the sweet ones are unfit for use in agues. Culpeper (1650) makes no mention of the fruit, but says of the flowers ‘... they stop fluxes and the Terms in women.’ In the Complete Herbal and English Physician (1826) says the fruit ‘... has the same general qualities as other acid fruits.’ Of the flowers he says (among other properties) that ‘A strong infusion of these cures ulcers in the mouth and throat, and fastens loose teeth.’ Gerard (1633) says that the cravings of pregnant women can be abolished with the juice, and perhaps it was scurvy which was being treated effectively when he reports that the juice was very effective against splitting of blood and for loose teeth. The dwarf form of this species, Punica granatum var. nana has fruits no more than 3cm across. Pomegranate bark can only be sold by registered pharmacies in the UK and used to be used as a vermifuge, with the secondary use that the tincture made from it doubled as a permanent ink. In South Africa the fruit rind is used for diarrhoea and stomach ache, and the bark as a vermifuge, but undesirable side effects make this dangerous. It is reported to be effective against fevers, as a diuretic, to lower blood sugar and to be both antibacterial and antiviral (van Wyk, 2000). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Anchusa azurea 'Loddon Royalist'
  • Tragopogon pratensis L. Asteraceae. Goatsbeard, Salsify, Jack-go-to-bed-at-noon. Distribution: Europe and North America. This is the Tragopogion luteum or Yellow Goats-beard of Gerard (1633) who recommended them boiled until tender and then buttered as being more delicious than carrots and parsnips and very nutritious for those sick from a long lingering disease. Boiled in wine they were a cure for a 'stitch' in the side. In the USA children collect the milky sap onto a piece of glass and, when dry, chew it as bubble-gum. The name 'Jack-go-to-bed-at-noon' referes to the flowers which close at noon and the spherical radiation of seed plumules which then appear. Salsify is now applied as a name for T. porrifolius and Scorzonera hispanica. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hyacinthoides non-scripta (L.) Chouard ex Rothm. Asparagaceae Bluebell. Perennial bulbous plant. Distribution W. Europe to N. Portugal. Seed and plants from wild stock are protected in England and Wales and all trade in them is prohibited, despite their abundance. All parts of the plant are poisonous and the sap can cause dermatitis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Dactylorhiza foliosa (Rchb.f.)Soo Orchidaceae Distribution: Madeira. Roots look like a hand and Coles (1657) calls them Palma Christi sive [or] Satyrion (to distinguish it from Ricinus communis which he calls Palma Christi sive Ricinus. This plant would be the closest to his Male Satyrion Royal, with purple flowers (but this is likely to be one of the English Marsh orchids,, and Dactylorhiza fuchsii is his Female Satyrion. In common with Orchis he writes 'The full and plump roots of the Satyrium or Orchis, whereof the Electuary Diasatyrium is made, are of mighty efficacy to provoke to venery, which they that have bulbous roots [meaning the testicle shaped roots of Orchis] do by Signature.'. Terrestrial orchids continue to be harvested by the millions annually in the Middle East for the production of Salep, including Salep ice cream, because of their mythological aphrodisiacal property. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Brugmansia suaveolens'Pink Beauty'
  • Cucurbita pepo L., Cucurbitaceae. Distribution: Mexico (extinct) This species is one of the oldest cultivated plants, first grown 11,000 years ago in Mexico, but extinct in the wild. Varieties are selectively bred for their taste, colour and shape. The seeds, ground to a powder are used to kill intestinal tape-worms (Lewis & Elvin-Lewis, 2003). This is a 200-year-old cultivar whose seed has been conserved by the Amish of Pennsylvania, USA. The rind is very thick, but the taste is delicious. This is a 200-year-old cultivar whose seed has been conserved by the Amish of Pennsylvania, USA. The rind is very thick, but the taste is delicious. Seeds approved for use in making herbal medicines in the UK (Herbal Medicine legislation 2013) Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Dianthus caryophyllus L. Caryophyllaceae Carnation, clove-gilliflowers - Mediterranean Culpeper (1650) writes that ‘Clove-gilliflowers, resist the pestilence, strengthen the heart, liver and stomach, and provokes lust.’ They smell strongly of cloves, and an oil made from the petals is used in perfumery, soaps etc. The petals are sometimes used as a garnish for salads. In herbal medicine they are used to make a tonic. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Petasites hybridus (L.)G.Gaertn., B.Mey. & Scherb. Asteraceae. Butterbur, Bog rhubarb. Distribution: Europe, NW Asia. Culpeper (1650) writes: “The roots are ... exceeding good in violent and pestilential fevers, they provoke the terms, expel poison, and kill worms.” Modern herbalists recommend it for a wide range of therapies, but it contains pyrrolizidine alkaloids, which are hepatotoxic and cause liver cancers. Nevertheless, in a trial aimed at reducing frequency of migraine attacks, a standardised commercial preparation was well tolerated, and was effective at higher doses, but placebo in this trial reduced migraines by over 50% in 49% of the patients (Neurology 2004
  • Lathyrus vernus (L.)Bernh. Papilionaceae previously Orobus vernus L. (Linnaeus, 1753) Spring vetchling. Distribution: Europe to Siberia. The seeds of several Lathyrus species are toxic, and when eaten cause a condition called lathyrism. The chemical diaminoproprionic acid in the seeds causes paralysis, spinal cord damage, aortic aneurysm, due to poisoning of mitochondria causing cell death. Occurs where food crops are contaminated by Lathyrus plants or where it is eaten as a 'famine food' when no other food is available. It is the Orobus sylvaticus purpureus vernus of Bauhin (1671) and Orobus sylvaticus angustifolius of Parkinson (1640) - who records that country folk had no uses for it. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hydrangea quercifolia W.Bartram Hydrangeaceae. Oak-leaved hydrangea. Distribution: South-eastern United States. Beta-dichroine a quinazolinone also called febrifugine from the leaves of hydrangeas is 64-100 times more potent than quinine as an antimalarial in animals, but extremely toxic. A synthesised tolyl derivative, methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone), was found to be a mild hypnotic, and marketed in the sleeping tablet, Mandrax. Widely abused and quickly banned by most countries. Illegal manufacture continues and in South Africa methaqualone is the commonest drug of abuse, mixed with cannabis and smoked. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Rosa 'Ispahan'
  • Chamaemelum nobile (L.) All. Asteraceae. English, Roman or garden chamomile Distribution: Europe, Mediterranean. Culpeper (1650): “... assuage swellings, inflammations of the bowels, dissolve wind, are profitable given in clysters or drink, to such as are troubled with colic or [renal] stone.” The leaves are pleasantly fragrant, hence its use as a lawn plant, but also in aromatherapy. A ‘tea’ made from the flowers is apparently used to lighten hair colour. Chamomile contains sesquiterpene lactones, and these are known to possess allergenic properties. Hypersensitivity reactions have been reported in this and other members of the Compositae (Asteraceae) and cross sensitivity reactions may occur (Medicines Control Agency, 2002). Analgesic, and used for cramps and spasms (Quincy, 1718). Chamomile tea is used to help sleep, but may cause uterine contractions so avoid in pregnancy (US National Institutes of Health advice). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Ricinus communis L. Euphorbiaceae Castor oil plant. Palma Christi. Distribution: Mediterranean, E Africa, India. The seeds themselves are pretty, brown, bean-like usually with gold filigree markings on them, and the interior of the seed is the source of castor oil. The outer coat of the seed is the source of the poison ricin, famous (infamous) for the umbrella murder of Georgi Markov on Waterloo Bridge in 1978. The KGB are alleged to have killed Georgi Markov, a dissident Bulgarian journalist, with a pellet containing 0.28mgm of ricin fired into his leg using a specially adapted air gun in an umbrella. While his symptoms were those of ricin poisoning, no ricin was ever found in the pellet that was extracted from his leg. Two seeds, chewed and ingested are said to be fatal, but most people vomit and get rid of the toxin. Ducks are resistant to ricin, and need to ingest more than 80 to be fatal! In Peru the leaves are used as a tea for stomach ache, although they contain small amounts of ricin. It is called Palma Christi in early herbals because of the five pointed leaves, which schematically represent a hand. It is a monotypic genus in the spurge family. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Cichorium intybus L., Asteraceae. Chicory, succory. Distribution: Uses: 'Cichory, (or Succory as the vulgar call it) cools and strengthens the liver: so doth Endive' (Culpeper, 1650). The Cichorium sylvestre, Wilde Succorie, of Gerard (1633) and the leaves cooked into a soup for ill people. Linnaeus (1782) reported it was used for Melancholia, Hypochondria, Hectica [fever], haemorrhage and gout. Root contains 20% inulin, a sweetening agent. Dried, roasted and ground up the roots are used as a coffee substitute, best known as Camp coffee (Chicory and Coffee essence). This used to be sold in tall square section bottle with a label showing a circa 1885 army tent with a Sikh soldier standing and serving coffee to a seated officer from the Gordon Highlanders. The bottle on the label has now moved on, and since 2006 it shows the same tent but the Sikh and the Scot are now both seated, drinking Camp coffee together. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Ribes odoratum H.L.Wendl Grossulariaceae Buffalo currant. Distribution: North America. Fruits edible. Presumably a source of vitamin C but no medicinal use. No reports of medicinal usage by Native Americans found. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Agapanthus 'Streamline'
  • Neottia ovata plus Cantharis rufipes beetle
  • Podophyllum peltatum (May apple or American mandrake)
  • Epimedium pubescens Maxim. Berberidaceae. Horny (sic) Goat Weed. Distribution: China. Marketed as an aphrodisiac, with the ability to act like sildenafil and for osteoporosis. Side effects reported include dizziness, dry mouth, vomiting and cardiac irregularity. It is not listed in Wiart (2006) or Wichtl (1994). Its reputation began, apparently, when a Chinese farmer observed increased sexual activity in his goats after they had been eating Epimedium. Given the enormous profits made by medicines such as sildenafil, it is indicative of its therapeutic value that it has not been taken up by a pharmaceutical company. Poor absorption from the gut and lack of information on toxicity may be responsible. It is not licensed for sale in the UK as a Traditional Herbal Remedy (Traditional Herbal Medicines Registration, January 2013) and has not been assessed or approved by the European Medicines Agency's Committee on Herbal Medicinal Products (HMPC). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Orchid flower (Phalaenopsis sp.)
  • Senecio pulcher Hook.&Arn. Asteraceae Distribution: South America. It has not attracted attention as a medicinal or toxic plant but members of the genus Senecio contain pyrrolizidine alkaloids that are toxic to the liver and may cause liver cancer. A traditional Chinese medicine (TCM) product, Qianbai Biyan Pian, contains Senecio scandens which contains the unsaturated pyrrolizidine alkaloids, senecionine and seneciphylline. This is now a banned drug. (Safety of Herbal Medicinal Products, July 2002, Medicines Control Agency). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Echinacea purpurea (L.) Moench Asteraceae. Coneflower. Distribution: North America. Austin (2004) records that the roots were chewed, or used as a tincture for coughs by the Choctaw. Combined with Rhus typhina to treat venereal disease by the Delaware. Very little record of this being used by Native Americans, who used E. angustifolia very widely - Regarded as a panacea and magical herb. This and E. pallida were used to treat snakebite, spider bite, cancer, toothache, burns, sores, wounds, flu and colds. E. purpurea in modern times has been used as an ‘immunostimulant’, but is known to cause a fall in white cell count, and to be purely a placebo. Licensed for use as a Traditional Herbal Medicine, which does not require proof of efficacy, in the UK. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physocarpus opulifolius (L.)Maxim. Roasaceae Distribution: North America. Austin () reported it was used for gynaecological problems by the Iroquois and Menomini