The organic constituents of plants and vegetable substances and their chemical analysis / by G.C. Wittstein ; authorised translation from the German original, enlarged with numerous additions, by Baron Ferd. von Mueller.

  • Georg Christian Wittstein
Date:
1878
Catalogue details

Licence: Public Domain Mark

Credit: The organic constituents of plants and vegetable substances and their chemical analysis / by G.C. Wittstein ; authorised translation from the German original, enlarged with numerous additions, by Baron Ferd. von Mueller. Source: Wellcome Collection.

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    soluble in water and partly of an oily nature.—Found by Howard in the bark of Cinchona succii-ubra.] Cinchoni(lill=:C20 H12 NO. In the Quina rubra granatensis (called originally Quina pseudoregia), from Cinchona succirubra, C. Calisaya, C. officinalis, C. lancifolia. Exhaust the bark reduced to powder, mth water acidulated by hydrochloric acid, treat the solution with milk of lime, collect the deposit, dry, pulverise, draw out with alcohol, evaporate the fluid, let crystallise and purify by recrystallising in alcohol.—Forms colourless, long, shining prisms j fuses at 167 to 170° and decomposes in higher temperatures; without smell, of bitter taste; becomes electric by friction; dissolves in 3287 parts cold, and in 596 parts boiling water, in 88 parts cold and in 19 parts boiling alcohol of 0.833, in 398 parts cold ether of 0*740; the alcoholic solution has an alkaline reaction; dissolves readily in diluted acids, also in concentrated sulphuric aoid without change; dissolves colourless in chlorine-water, and ammonia produces in the solution a grey- white precipitate, soluble in an excess of ammonia ^vith pale sherry colour. It saturates the acids completely, and forms well crystallisable salts, which are permanently precipitated by caustic alkalies and their carbonates, phosphate of soda, chloride of mercury, chloride of platinum, cliloride of gold, iodide of potassium, sulphocyanide of j)otassium, nitrate of palladium and by tannic acid. Cinclioiiidin^:Pasteur's Quinidin. Cinchollill=C2o II12 NO. Prevails in the grey and brown and especially in the Huanoko Quina-barks, from Cinchona micrantha, C. nitida, C. Peruviana, C. Pahudiana, C. scrobiculata, C. cordifolia. Digest with water acidulated with hydrochloric acid, press, concentrate the extracts, filter, precipitate with ley of soda, wash the deposit and dissolve it in acetic acid, precipitate again, dry the deposit, boil with alcohol and allow to crystallise.—Forms white pellucid needles of alkaline reaction, of slightly bitter taste, fuses only when decomposition is setting in, and evaporates partly undecomposed (according to others : it fuses at 150 to 160° and sublimates partly in white needles); dissolves in 3670 parts cold, and in 2500 parts boiling water, in 126 parts absolute, and in 115 parts alcohol of 90% at 15°, in 40 parts boiling alcohol, in 600 parts cold and in 470 parts boiling ether, in 23 parts chloroform, little in oils ; dissolves colourless in chlorine- water, and is precipitated white by ammonia ; dissolves colourless in concentrated sulphuric acid and is not coloured on heating; insoluble in alkalies. Neutralises the acids and yields mostly crystallisable salts, the solutions of which turn dark red- brown in the sunlight.
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