Blood : a study in general physiology / by Lawrence J. Henderson.

  • Lawrence Joseph Henderson
Date:
1928
Catalogue details

Licence: In copyright

Credit: Blood : a study in general physiology / by Lawrence J. Henderson. Source: Wellcome Collection.

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    servations of our own. In order to make the facts as clear as possible, it will be necessary to explain the position of the curve as a function of hydrogen ion concentration. To this end, a roughly approximate mathematical treatment of the problem may be employed. In the absorption of oxygen four substances are as¬ sumed to be involved: Hb, Hb02, Hb~, and Hb02“- Let [Hb02] + [HbO,-] = C, (1) and [Hb] + [Hb-] = 100 - C. (2) We have, approximately, k - [Hb] • nn ku ~ [Hb02] P ’ (3) and k- [Hb'] n (4) Also [Hb] _ [H+] _io818-rH+l [Hb-] kR ~ 1 J’ (5) and [Hb02] _ [H+] _in6-62-rH+l [Hb02-] k0 1 J‘ (6) From equation 5, [Hb] = 1081S • [H+]*[Hb-]. (7) From equation 6, [Hb02] = 106 62 • [H+] • [Hb02-]. (8) From equations 2 and 7, [Hb-] + 10818 • [H+] • [Hb-] = 100 - C. From equations 1 and 8 Whence and [Hb02] + 106 62 • [H+] • [Hb02-] = C. r-Rh 1 - 100 -c L±1D j _ i + 1()8.18.[H+]' Q [Hb02] = j_|_ io6-62-[H+]’ (9) (10)
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