The constituents of the seeds of Hydnocarpus wightiana, Blume, and of Hydnocarpus anthelmintica, Pierre / by Frederick B. Power and Marmaduke Barrowcliff.

Frederick Belding Power

Date:: [1905]

Credit: The constituents of the seeds of Hydnocarpus wightiana, Blume, and of Hydnocarpus anthelmintica, Pierre / by Frederick B. Power and Marmaduke Barrowcliff. Source: Wellcome Collection.

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$The mother liquor from the latter acid afforded a large fraction consisting of a pasty solid which could not be crystallised. It was found, however, that by washing with cold alcohol the acids of an oily character were removed, and that the undissolved portion could then be readily crystallised by dissolving in warm alcohol. A large fraction melting at 46—48° was thus obtained, which was apparently identical with the molecular mixture of chaulmoogric and hydnocarpic acids obtained from Hydnocarpus Wighticma and II. anthelmintica. By fractional precipitation with barium acetate, the two acids were readily separated, and hydnocarpic acid, melting at 59—60°, definitely identi¬ fied as a constituent of the fatty oil of Tccraktogenos seeds. 0*1221 gave 0*3405 C02 and 0*1222 H20. C = 76*l ; H=ll*l. Ci0H28O2 requires 0 = 76*2; H = 11*1 per cent. 0*1346 absorbed 0*1338 iodine. 1 = 99*4. C16H2S02, with one ethylenic linking, requires 1 = 100*7 per cent. A solution of 1*2652 in chloroform, made up to 25 c.c., gave in a 1-dcm. tube aD +3°26', whence [a]D +67*8°. We desire to express our thanks to Mr. Frederic H. Lees for his assistance in connection with the investigation of these oils. The Wellcome Chemical Research Laboratories, London, E.C. K. CLAV AND SONS LTD. HRKAD 8T. HILL, F.C., ANI) BUNGAY, SUFFOLK$