A contribution to the knowledge of protection against infectious diseases / by Alfred Lingard ; communicated by E. Klein.
- Alfred Lingard
- Date:
- [1889]
Licence: Public Domain Mark
Credit: A contribution to the knowledge of protection against infectious diseases / by Alfred Lingard ; communicated by E. Klein. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![1888.] Protection against Infectious Diseases. VII. The shortest period observed interveniiig between the inocu- lation of the foetus in utero and parturition, after which the mother was found to be protected against the inoculation of virulent anthrax blood, was thirty-six hours. VIII. For the protection of the surviving foetuses, or those other than the one primarily inoculated with anthrax in utero, a longer exposure is required than the minimum thirty-six hours observed to protect the mother. Or the surviving foetuses may have received pro- tection, provided that a period of not less than six days have elapsed between the primary inoculation of the foetus in utero and parturi- tion. IX. In those cases where the mother died of anthrax contracted at the time of the inoculation of the foetus in utero, and excepting the last-mentioned one, the heart's blood of the other foetuses in utero was not found to contain any anthrax bacilli, as proved by cultivations when the examination was made, several hours after the death of the mother. But if the examination and cultivations were made some sixty or seventy hours later, then any or all of the foetuses, according to the temperature of the air prevailing, may have anthrax bacilli in their blood. [X. The inoculation of a foetus in utero with anthrax may produce one of three results :— (i ) If during the inoculation of a foetus the anthrax bacilli gain entrance into the tissues of the mother, owing to imperfect manipulation, the mother naturally succumbs to the disease, (ii.) In some cases the organisms pass through from the foetal to the maternal vessels; this is probably due to some change taking place in the placental tissues, either inflammatory or traumatic in orisrin. (iii.) Lastly, in those cases where the foetus alone is inoculated, the mother remains free from the bacillary disease, and at a later date is found to have acquired immunity.—Jan. 22,1889.] XI. In sections of the placenta of the foetus primarily inoculated with anthrax in ute^-o, and through which the mother received pro- tection, the anthrax bacilli, after staining with aniline dyes, are to be seen wholly in the foetal, while there is a total absence of them in the maternal portion. HAEElaON AND SONS, PEINTEBS IN OBDINAEY TO HEB HAJESTr, ST. MAETIN'S LANE.](https://iiif.wellcomecollection.org/image/b22279866_0005.jp2/full/800%2C/0/default.jpg)
