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  • Rhododendron yakushimanum 'Grumpy'
  • Hepatica nobilis Mill. Ranunculaceae. Liverwort - not to be confused with the lichen of the same name. Distribution: North America. Liverwort (‘liver plant’): discontinued herbal medicine for disorders of the liver. The name and the use to which the Liverworts have been put medicinally is suggested, according to the doctrine of signatures, by the shape of the leaves which are three-lobed, like the liver. It is little used in modern herbalism but was employed in treating disorders of the liver and gall bladder, indigestion etc. It is highly toxic. Hepatica acutiloba was widely used for liver disorders in the 1880s, with up to 200,000 kilos of leaves being harvested per annum to make liver tonics - which eventually caused jaundice. Gerard (1633) calls it Hepaticum trifolium, Noble Liverwort, Golden Trefoile and herbe Trinity and writes: 'It is reported to be good against weakness of the liver which proceedeth from a hot cause, for it cooleth and strengtheneth it not a little. ' He adds ' Baptista Sardus [a Piedmontese physician fl. 1500] commendeth it and writeth that the chiefe vertue is in the root
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Paeonia officinalis (Peony)
  • Alcea rosea 'Nigra'
  • Paeonia officinalis 'Flore Pleno'
  • Erythroxylum coca Lam. Erythroxylaceae Coca. Distribution: Peru . Cocaine is extracted from the leaf. It is no longer in the UK Pharmacopoeia (used to be used as a euphoriant in ‘Brompton Mixture’ for terminally ill patients). Cocaine, widely used as a local anaesthetic until 1903, inhibits re-uptake of dopamine and serotonin at brain synapses so these mood elevating chemicals build up and cause a ‘high’. Its use was often fatal. Coca leaf chewing was described by Nicolas Monardes (1569
  • Ajuga reptans 'Pink Elf'
  • Vitex agnus-castus var. latifolia
  • Serratula tinctoria subsp. seoanei (Willk.)M.Lainz Asteraceae. Saw-wort (in the USA called Dyer's plumeless saw-wort). Distribution: Europe. Named after Dr Victor Lopez Seoane (1832-1900) a Spanish naturalist and physician who was Professor of Physics, Chemistry and Natural History in Corunna. He attained a certain infamy in that three of the subspecies of birds which he published as new discoveries were in leaflets dated 1870 and 1891 but were actually published in 1894, the discovery of which rendered two of his discoveries attributable to others (Ferrer, in Ingenium 7:345-377 (2001). This plant was described by Heinrich Willkomm in 1899 as Serratula seoanei, but M. Lainz, in 1979, decided it was merely a subspecies of Serratula tinctoria, a plant described by Linnaeus (1753). Linnaeus based his description on a plant with a woodcut in Dodoens' Pemptades (1583), saying it had pinnate leaves. However, that woodcut is of two different plants, and when re-used by Gerard (1633) he pointed out that Tabernamontanus (1625) had a woodcut of them and a third plant all with leaves varying from just pinnate to entire. Whatever, the leaves on Serratula tinctorius subsp. seoanei are very distinct, but while pinnate the leaflets are exceedingly narrowly and deeply dissected, Gerard (1633) writes that it is 'wonderfully commended to be most singular [useful] for wounds, ruptures, burstings, and such like...' It is a dye plant, containing luteolin, the same yellow dye as is present in Reseda luteola (source of the dye 'weld'). Seoane also has a viper, Vipera seoanei, named after him
  • Paeonia officinalis L. Paeoniaceae, European Peony, Distribution: Europe. The peony commemorates Paeon, physician to the Gods of ancient Greece (Homer’s Iliad v. 401 and 899, circa 800 BC). Paeon, came to be associated as being Apollo, Greek god of healing, poetry, the sun and much else, and father of Aesculapius/Asclepias. Theophrastus (circa 300 BC), repeated by Pliny, wrote that if a woodpecker saw one collecting peony seed during the day, it would peck out one’s eyes, and (like mandrake) the roots had to be pulled up at night by tying them to the tail of a dog, and one’s ‘fundament might fall out’ [anal prolapse] if one cut the roots with a knife. Theophrastus commented ‘all this, however, I take to be so much fiction, most frivolously invented to puff up their supposed marvellous properties’. Dioscorides (70 AD, tr. Beck, 2003) wrote that 15 of its black seeds, drunk with wine, were good for nightmares, uterine suffocation and uterine pains. Officinalis indicates it was used in the offices, ie the clinics, of the monks in the medieval era. The roots, hung round the neck, were regarded as a cure for epilepsy for nearly two thousand years, and while Galen would have used P. officinalis, Parkinson (1640) recommends the male peony (P. mascula) for this. He also recommends drinking a decoction of the roots. Elizabeth Blackwell’s A Curious Herbal (1737), published by the College of Physicians, explains that it was used to cure febrile fits in children, associated with teething. Although she does not mention it, these stop whatever one does. Parkinson also reports that the seeds are used for snake bite, uterine bleeding, people who have lost the power of speech, nightmares and melancholy. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Tiger Lily
  • Allium schoenoprasum L. Alliaceae. Chives. Bulbour perennial herb. 'schoenoprasm' means 'rush leek' in Greek, referring to the narrow leaves. Distribution: Asia, Europe and North America. Leaves used as a garnish on cooked food and in salads. However like others in Boraginaceae it contains the pyrrolizidine alkaloid cynoglossine which causes liver damage. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Paeonia officinalis 'Flore Pleno'
  • Crocosmia x crocosmiiflora 'Emily McKenzie'
  • Osmanthus delavayi Franch. Oleaceae Evergreen shrub. Distribution: China. Osmanthus is derived from the Greek for 'fragrant flower', delavayi from its discoverer, the French Missionary with the Missions Étrangères, and plant collector, Pierre Delavay (1834-1895). He sent 200,000 herbarium specimens containing 4000 species including 1,500 new species to Franchet at the Museum of Natural History in Paris. He sent seed of O. delavayi to France (1886), but only one germinated, and all the plants in cultivation until it was recollected 40 years later, arose from this plant (Bretschneider, 1896). The flowers are used to make a tea in China, but the berries (drupes) are not regarded as edible. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Xanthorhiza simplicissima Marshall Ranunculaceae. Yellow root. Distribution: North America, where it was discovered by the plant collector and explorer William Bartram in 1773. Yellow-root. Austin (2004) reports that of the Native Americans, the Cherokee use the crushed plant to make a yellow dye
  • Matthiola incana (L.)W.T.Aiton Brassicaceae Distribution: The genus name commemorates Pietro Andrea Mattioli (1500/1–77), physician and botanist, whose name is Latinised to Matthiolus.. Incana means hoary or grey, referring to the colour of the leaves. Mattioli's commentaries on the Materia Medica of Dioscorides were hugely popular. Matthiola incana was first described by Linnaeus as Cheiranthus incanus, being changed to Matthiola by William Aiton, at Kew, in 1812. It is in the cabbage family. Commercial seed packets contain a mixture of single and double forms. The latter are sterile, but selective breeding has increased the proportion of double forms from the seed of single forms to as much as 80%. ‘Ten week stocks’ are popular garden annuals, flowering in the year of sowing, whereas ‘Brompton stocks’ (another variety of M. incana) are biennials, flowering the following year. Gerard (1633), called them Stocke Gillofloure or Leucoium, and notes the white and purple forms, singles and doubles. About their medicinal value he writes ‘not used in Physicke except among certain Empiricks and Quacksalvers, about love and lust matters, which for modestie I omit’. The thought of a member of the cabbage family being an aphrodisiac might encourage the gullible to take more seriously the government’s plea to eat five portions of vegetable/fruit per day. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Geranium maderense Yeo Geraniaceae Tender evergreen biennial. Madeira cranesbill. Distribution: Madeira. Solely grown for its spectacular flowers. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Rosa damascena Mill. Rosaceae Distribution: Garden origin. A hybrid between R. gallica and R. moschata.. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Dahlia merckii
  • Oenothera macrocarpa Nutt. Onagraceae. Ozark Sundrops, Bigfruit Evening Primrose. Formerly O. missouriensis. Distribution: South central USA. O. macrocarpa does not appear to have been used medicinally, but other species are so used. Austin (2004) records that O. biennis (Evening Primrose) was used by Native Americans as a potherb in West Virginia. Leaves as salad, roots boiled like potato also infusion to treat obesity and relieve piles (Cherokee)
  • Athyrium niponicum (Mett.) Hance var. pictum (Maxwell) Fraser-Jenk. Woodsiaceae. Japanese Painted fern. Hardy fern. Distribution: Japan. Young fronds are boiled and eaten in Japan. However after the discovery of thaiminases in certain ferns Pteridum aquilum (bracken), Marsilea drummondii and Cheilanthes sieberi cautions are given regarding the risk of thiaminase in all ferns. It can be mostly removed by boiling, but otherwise causes vitamin B1 (thiamine) deficiency and beriberi in a matter of weeks. Eating Bracken fern also causes cancer, as do the spores, but I could find no report of other ferns being toxic. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Sanguinaria canadensis (Bloodroot, Pucoon or Indian paint)
  • Tanacetum cinerariifolium Sch.Blp. Asteraceae Dalmation chrysanthemum, Pyrethrum, Pellitory, Tansy. Distribution: Balkans. Source of the insecticides called pyrethrins. The Physicians of Myddfai in the 13th century used it for toothache. Gerard called it Pyrethrum officinare, Pellitorie of Spain but mentions no insecticidal use, mostly for 'palsies', agues, epilepsy, headaches, to induce salivation, and applied to the skin, to induce sweating. He advised surgeons to use it to make a cream against the Morbum Neopolitanum [syphilis]. However he also describes Tanacetum or Tansy quite separately.. Quincy (1718) gave the same uses
  • Ricinus communis L. Euphorbiaceae Castor oil plant. Palma Christi. Distribution: Mediterranean, E Africa, India. The seeds themselves are pretty, brown, bean-like usually with gold filigree markings on them, and the interior of the seed is the source of castor oil. The outer coat of the seed is the source of the poison ricin, famous (infamous) for the umbrella murder of Georgi Markov on Waterloo Bridge in 1978. The KGB are alleged to have killed Georgi Markov, a dissident Bulgarian journalist, with a pellet containing 0.28mgm of ricin fired into his leg using a specially adapted air gun in an umbrella. While his symptoms were those of ricin poisoning, no ricin was ever found in the pellet that was extracted from his leg. Two seeds, chewed and ingested are said to be fatal, but most people vomit and get rid of the toxin. Ducks are resistant to ricin, and need to ingest more than 80 to be fatal! In Peru the leaves are used as a tea for stomach ache, although they contain small amounts of ricin. It is called Palma Christi in early herbals because of the five pointed leaves, which schematically represent a hand. It is a monotypic genus in the spurge family. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Carpobrotus acinaciformis (L.) L.Bolus Aizoaceae. Eland's Sour fig. Sally-my-handsome, its other common name is a corruption of Mesembryanthemum (acinaciforme) which was the genus ascribed to it by Linnaeus (1753) Succulent perennial. Distribution: South Africa. Antibacterial compounds have been isolated from it, it is rich in tannins. The leaf sap is used to treat infections of the mouth and throat. In South African ‘muthi’ medicine, the sap is used as a gargle for sore throats
  • Punica granatum L. Lythraceae Pomegranate, granatum malum, balustines. Distribution: E. Mediterranean to Himalayas. The Pomegranate is in the centre of the Arms of the Royal College of Physicians, perhaps for its use in cooling, and therefore for fevers. However it was the sour pomegranate that would have been used as Dioscorides says the sweet ones are unfit for use in agues. Culpeper (1650) makes no mention of the fruit, but says of the flowers ‘... they stop fluxes and the Terms in women.’ In the Complete Herbal and English Physician (1826) says the fruit ‘... has the same general qualities as other acid fruits.’ Of the flowers he says (among other properties) that ‘A strong infusion of these cures ulcers in the mouth and throat, and fastens loose teeth.’ Gerard (1633) says that the cravings of pregnant women can be abolished with the juice, and perhaps it was scurvy which was being treated effectively when he reports that the juice was very effective against splitting of blood and for loose teeth. The dwarf form of this species, Punica granatum var. nana has fruits no more than 3cm across. Pomegranate bark can only be sold by registered pharmacies in the UK and used to be used as a vermifuge, with the secondary use that the tincture made from it doubled as a permanent ink. In South Africa the fruit rind is used for diarrhoea and stomach ache, and the bark as a vermifuge, but undesirable side effects make this dangerous. It is reported to be effective against fevers, as a diuretic, to lower blood sugar and to be both antibacterial and antiviral (van Wyk, 2000). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Scabiosa columbaria L. Dipsacaceae. Small scabious. Distribution: Europe. Culpeper (1650) writes: ‘The roots either boiled or beaten into powder and so taken, helps such as are extremely troubled with scabs and itch, are medicinal in the French-pocks [syphilis], hard swellings, inward wounds ...’ The genus name comes from the Latin word scabies, meaning ‘itch’. According to the Doctrine of Signatures, the rough leaves indicated that it would cure eczematous skin. However, the leaves are not really very rough... Not used in herbal medicine at the present time except in Southern Africa where it is used for colic and heartburn, and the roots made into an ointment for curing wounds (van Wyk, 2000). Photographed in the Medicinal Garden of the Royal College of Physicians, London.