The prevention of malaria.

  • Ronald Ross
Date:
1910
Catalogue details

Licence: In copyright

Credit: The prevention of malaria. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

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    were liberated from bottles in houses free from mosquitos, and search was made to ascertain what became of them. Only 54, or 16%, were found, mostly dead, during the next day or two, after which the remainder disappeared entirely. Only three persons were bitten after the experiment—suggesting that the biting ratio (section 29 (3)) is very low, say 1/50. (5). We have found three more successful mosquito inoculations of man, bringing the number up to 38 (section 17). Case 36. J. Tsuzuki [1902].—Source, benign tertian. One of many infected Myzorh. sinensis bit healthy subject in Sapporo, Jeso, Japan, which is free of malaria on 24th August (?) 1901. Fever and parasites on 31st August. Case 37. N. Janscd [1903].—Source, malignant. A. claviger (? Meig.) bit subject on 6th December 1907 in Hungary. One gramme sulphate of quinine given on seventh and eighth day after inoculation. Fever and parasites on 18th December. Case 38. Ibid.—Same source and one A. claviger. Subject given same dose of quinine on eighth, ninth and tenth days after inoculation on 20th and 25th October (? year). Fever on 4th November and parasites on the 5 th. Janscd also records three interesting negative cases obtained at the same time. Case 1 received 1 gramme of quinine daily from the second to the fourteenth day after inoculation, and remained well during nine months' incubation. Case 2 received 1/2 gramme every morning on an empty stomach from ten hours before inoculation to the thirteenth day afterwards, and remained well during one month's observation. Case 3 received 1*5 grammes quinine on fourth, fifth, ninth, tenth, fourteenth and fifteenth days after inoculation, and had no fever during one month's observation. M. Glogner [1905] records two cases which he thinks were due to inoculation during vaccination. (6). With reference to the attitude of Anophelines, Mr Theobald informs me that the only species known to him of which the larva suspends itself in water like a Culicine larva is Myzomyia azriki Patton, 1905 ; and that Myzomyia culicifacies is the only one of which the adult has an abnormal attitude. So far as he knows the larvae of all the species have no siphon.