The integration of the endocrine system : being the fifth Horsley memorial lecture, delivered at the University College Hospital Medical School / by Sir Walter Langdon-Brown.

  • Walter Langdon-Brown
Date:
1935
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Licence: In copyright

Credit: The integration of the endocrine system : being the fifth Horsley memorial lecture, delivered at the University College Hospital Medical School / by Sir Walter Langdon-Brown. Source: Wellcome Collection.

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    diencephalon, and producing an activating and an inhibitory hormone of a protein character according to demand, which can speed up or inhibit the secretion of the simpler grade of hor¬ mone in the other endocrine glands; hormones which are of allied chemical structure and which in some instances may even be interchangeable in their action. At any rate it is a unifying hypo¬ thesis which deserves further and careful con¬ sideration. Antihormones. The question has not been sim¬ plified by the claims made for the existence of antihormones. Collip showed some time ago that parathormone gradually lost its effect on repeated injections. One might imagine that this failure could be adequately accounted for by its destructive action on the calcium content of bone and muscle, but he now18 thinks that there is an antihormone both to the pituitary growth and thyrotropic hormones, and advances the hypo¬ thesis that the production of antihormones may be responsible for hypoglandular states. He regards a hormone-antihormone linkage as the normal condition, which can readily be disturbed.
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