Leprosy : summary of recent work no. 6.

Date:: 1925

Credit: Leprosy : summary of recent work no. 6. Source: Wellcome Collection.

9/20 page 103

$1906, but without success. Later he had another failure with HEISER’s intramuscular injections of the oil, which only produced some improve- ment in the general health of the lepers after 22 months careful trial, although J. Witson at Kwangju, in Korea, is now reporting good results with injections of large doses of the Chinese Hydunocarpus anthelmintica oil. Next, RoGERS’ sodium hydnocarpate and morrhuate were used, and are still in use in parts of China in spite of more potent remedies being now available; “reports as to curative resuits are somewhat conflicting, but on the whole positive in character.”’ Recently the esters of Chaulmoogra and Hydnocarpus oils have been used, with undoubtedly the most successful results so far, in some 43 China stations from which reports have been received, although no statistical tables of the cures obtained can yet be given ; the earlier the case and the younger the patient the better is the prognosis. Chronic cases improve to some extent and lose the former characteristic disagreeable odour of leper homes, while their general health improves. Moogrol and the triply distilled Pekin Union Medical College esters, plus a 20 per cent. solution of creosote in camphor oil, or 20 to 25 per cent. pure camphorated oil, have proved best in doses increased to the point of tolerance of the patient, which varies widely. Prolonged oral administration of the esters produces fatty degeneration as shown by B. E. Reap. Tartrate of antimony has not been successful in China, and the ethyl ester chauimoograte treatment holds the field, although it often fails in sub-acute and chronic cases and in some early ones. Finally, he thinks a combination of segregation and treatment is necessary, but very difficult to carry out in present Chinese conditions. 120. VurPILLat (Ff. J.). The Use of Extractives of Chaulmoogra and Cod-Liver Oils in Leprosy and Tuberculosis—U.S. Nav. Med. Bull. 1925., May. - Vol. 22...No.5.. pp. 587-594. _. [20 refs] The author gives a good epitome of the published work from that of ROGERS in 1916 to date, and rernarks that the available literature is remarkably small considering the importance of the therapy of acid-fast organisms. He believes further experimental and clinical trial of these substances is warranted in tuberculosis, with which he chiefly deals. gal Aox! (Taiyu), Kawamura (Kasayuki), Kamikawa (Yutaka) & FuKa- MACHI (Roan). {On the Intravenous Injection of Derivatives of Chaulmoogra Oil against Leprosy. III.|— Hifuka Hitsunyokika Zasshi Gil. > Demmaty.e@ “Urol. A924., Apr. Vol. 24; INo. 5 4:)\ (Sum- imanized, in) {/aopanw Med... Word. 1925... Apres 1d.0°WVol.S; .No. 4. p. 108.1 This report deals with onlv 45 cases treated with four different prepara- tions with improvement in 11. No details of the stage of the disease are given. Lek. Matcomson (J. E.). Leprosy.— U.S. Nav. Med. Bull. 1925. May. Vol. 22. No.5. pp. 594-598. Two years’ treatment of 68 cases in the Virgin Islands is reviewed, 26 patients who refused treatment serving as controls. Careful$

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