Micro-organisms of the human mouth : the local and general diseases which are caused by them / by Willoughby D. Miller.
- Date:
- 1890
Licence: Public Domain Mark
Credit: Micro-organisms of the human mouth : the local and general diseases which are caused by them / by Willoughby D. Miller. Source: Wellcome Collection.
Provider: This material has been provided by the University of Toronto, Harry A Abbott Dentistry Library, through the Medical Heritage Library. The original may be consulted at the Harry A Abbott Dentistry Library, University of Toronto.
353/400
![Malassez and Galippe have made very careful investigations concerning the etiology of pvorrhcea alveolaris. Galippe con- siders the disease as undoubtedly of a parasitical nature, which m.iy be proved by an examination of stained sections, by culti- vation and isolation of the parasites contained in the dentinal tulmles, by the contagion spreading from tooth to tooth, as well as from individual to individual, as we have observed more than once in persons of difterent sex, who stand in intimate relations to each other. Galippe ^^^ found in the tubules of a tooth attacked by infectious arthro-dental gingivitis a parasite temporarily designated by the letter 35/, which shows the form of a very delicate double bubble (Doppelblaschen), and is changed by cultivation into a bacillus, the gelatine melting, and a characteristic rod appearing in the tube of the gelatinous bubble. '' Subcutaneously injected into guinea-pigs it produced, after fifteen days, in the joints of all the paws a series of abscesses, which made all motion impossible; the movements proceeding fr(mi tlie pelvis were extremely painful. Some of the abscesses opened spontaneously, the others were lanced with the necessary precautions. The parasite r^ could again be isolated from the pus. After several months the guinea-pig recovered from the infection, but the awkwardness and stiffness in the joints remained. This parasite showed a preference for the osseous system in a rabbit, into whose abdomen a pure culture of it was injected. After fifteen days the emaciated rabbit manifested a sluggishness of locomotion, and we discovered a considerable abscess in the plane of the left thigh. This abscess was lanced; from the pus treated in the usual manner the parasite y] was again obtained in pure culture. After a few days the abscess reappeared, and it was observed at the same time that the animal breathed with difficulty. Emacia- tion and depression increased, and the animal was killed about a month after inoculation. The examination of the heart and lungs revealed nothing particular; the kidneys were sound. The injection had caused no inflammation, either in the diges- tive organs or on the diaphragm. An enormous abscess occupied the entire posterior surface of the liver. The lower portion of](https://iiif.wellcomecollection.org/image/b2120293x_0353.jp2/full/800%2C/0/default.jpg)
