Licence: Public Domain Mark
Credit: An introduction to pathology and morbid anatomy / by T. Henry Green. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![A large growth is usvia]ly divided into several lobes by bands of fibrous tissue, in wbicb are contained the blood- vessels. These lobes are often very distinct, so that the growth appears to be made up of several separate tumours. Eibrous tissue in most cases also encapsules the growth, and separates it from the surrounding structures; hut sometimes this capsule is absent, and the tumour is surrounded by a zone of embryonic cells, which infiltrate the adjacent tissues. DEVELOPMENT.—The chondromata most frequently originate from common connective-tissue and bone, very rarely from cartilage. Cartilage itself, and especially fibro-cartilage, is very closely allied to common connective- tissue. It grows from the deeper layers of the peri- chondrium, which proliferate and form an embryonic tissue; the young cells become cartilage-cells, and these probably form the matrix, which is either homogeneous or fibriliated, constituting in the one case hyaline, and in the other fibro-cai-tilage. The development of choni droma from connective-tissue is precisely similar to the physiological progress. In the development of chrondroma from osseous tissue, the medulla is the source of the new growth. This pro- liferates and forms embryonic tissue, which absorbs tra- beculse and occupies the resulting space; cai-tilage is formed from it, as above. The mass gradually increases, a layer of fibrous tissue is formed around it, and further growth takes place from the tissue of the capsule. Vir- chow has shown that islands of cartilage not uncommonly remain in the shafts of bones, and has rendered it pro- bable that many chondromata spring from them. They generally begin before the ossification of the epiphyses, whilst the bone is actively growing and vascular. Lastly, cartilaginous growths may originate from car- tilage itself. These are sometimes seen on the surface of the articular cartilages, in the larynx and trachea, and on the costal and intervertebral cartilages. They are simply local overgrowths from pre-existing cartilage.](https://iiif.wellcomecollection.org/image/b21915842_0169.jp2/full/800%2C/0/default.jpg)
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