Elements of human physiology / by L. Hermann ; translated from the sixth edition by Arthur Gamgee.

  • Gamgee Arthur, 1841-1909.
Date:
1878
Catalogue details

Licence: Public Domain Mark

Credit: Elements of human physiology / by L. Hermann ; translated from the sixth edition by Arthur Gamgee. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

    61/620 (page 41)
    adding- hydrochloric acid. Hippuric acid separates in the form of a highly-coloiu-ed crystalline mass. This may be purified by solu- tion and decolorization with animal charcoal. Other aromatic acids possess the power, like benzoic acid, of linking themselves to glycocine in the system, and of forming compounds analogous to hippmic acid. Thus, after salicylic acid CyHgOg has been introduced into the body, salicyluric acid C9H9]S'04 is excreted in the urine. The latter acid readily decomposes into glycocine and salicylic acid ; thus— O^HgNO, + H,0 = O^H.NO, + V Y T ' ' Salicyluric acid Glycocine Salicylic acid Similarly, in passing through the system, anisic (formobenzoic- acid) is converted into anisuric acid, and toluic into tolmic acid. 9. Alanine, amido-proprionic acid, 03H4(NH2)O.OH, does not occur in tlie- animal body. 10. Butalanine, aniido-valerianic acid, 05Hg(NH2)O.OII, is said to accom-- pany leucine in some animal tissues. 11. Leucine, or amidocaproic acid, CgH[jQ(]S'H2)0.0H, occurs as a constituent of many glandular organs, and especially of the- pancreas. It is a constituent of the urine in certain diseases, especially in acute yellow atrophy of the liver, and is one of the products of the decomposition of the proteids by the pancreatic proteolytic ferment, being, however, also produced during the putrefactive decomposition of the proteids and by the action of strong acids and alkalies upon them. Leucine is soluble in 27 parts of cold water; it is very spar- ingly soluble in cold and hot alcohol. It crystallises from its solution in nodules and balls, which sometimes exhibit radiating- markings, and which occasionally are formed of radially arranged plates. Leucine melts at 170° and may be sublimed. 12. Se)-ine is probably amidolactic acid 03H5(NH2)03, and is obtained, in, addition to leiicine and tyrosine, when silk-gelatine is boiled witli acids. When treated with nitrous acid it yields oxylactic acid or glyceric: acid. 13. Cystine CgH^NSOg has been considered as serine, in which one atom of oxygen has been replaced by S, and as having pro- bably the same constitution. It is a constituent of the kidneys,, and is occasionally found in the urine and in urinary calculi. The formula of cystine is probably CgHgNSOg; when decomposed by means of nitrous acid it does not yield glyceric acid, as would almost certainly be the case if it were derived from serine (Dewar- and Gamgee).