Normal human blood serum as a curative agent in hemophilia neonatorum : a preliminary report, with suggestions for its use in other conditions / by John Edgar Welch.

  • Welch, John Edgar.
Date:
1910
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Licence: In copyright

Credit: Normal human blood serum as a curative agent in hemophilia neonatorum : a preliminary report, with suggestions for its use in other conditions / by John Edgar Welch. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    one day after bleeding began, 10 c.c. in one dose; on the sixth day, 20 c.c. in two doses; on the ninth day, 20 c.c. in two doses; on the tenth day, 10 c.c. in one dose; on the eleventh day, 8 c.c. in one dose; on the twelfth day, 5 c.c. in one dose; on the thirteenth day, 10 c.c. in one dose; total, 83 c.c. in seven days (Fig. 7). The bleeding in each attack was controlled on the second day. This chart illus- Fio. 7.—Temperature and weight charts of Case VII. trates twice the manner in which the temperature and weight curves diverge during the bleeding, and how they approach each other when bleeding stops. Case VIII.—First child; male; full term; normal labor. On the third day began bleeding from the mouth and rectum. On the fourth day profuse bleeding from the mouth, nose, rectum, and under the skin covering the left scapula. On the fifth day bleeding continued. No bleeding on the sixth day. On the seventh day bleeding from the rectum. No bleeding after the seventh day. Normal human blood serum was injected subcutaneously as follows: On the sixth day, three days after bleeding began, 7 c.c. in one dose; on the seventh day, 9 c.c. in one dose; total, 16 c.c. in two days (Fig. 8).
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