Experimental researches on the central localization of the sympathethic with a critical review of its anatomy and physiology / by B. Onuf and Joseph Collins.

  • Onuf, Bronislaw.
Date:
[Utica, N.Y.] :
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Credit: Experimental researches on the central localization of the sympathethic with a critical review of its anatomy and physiology / by B. Onuf and Joseph Collins. Source: Wellcome Collection.

Provider: This material has been provided by King’s College London. The original may be consulted at King’s College London.

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    norma] that may be found in the oblongata in these cases, and we fully realize that some of them may be accidental, and merely dependents of functional disturbance. Never- theless, recent histological technic has shown that they are of greater importance than has previously been thought. Gowers says it is possible that some of the cardiac disturbance is produced through the agency, not of the sympathetic, but of the vagus. It is well here to bear in mind that Jendrassik has recently contended for the admission of the vagus to the sympathetic system and its removal from the domain of the cerebro-spinal nerves. If this be allowed, it will be recognized that no essential discrepancy exists in these views. Concerning the morbid findings in cases of Graves' Dis- ease, Mobius has recently written: All sorts of con- ditions have been described; the ganglia are too large or too small; the nerve too thick or too thin; there is too much connective tissue, or too few nerve cells; the nerve cells are deformed, shrunken, or pigmented; there are small hemorrhages, destruction of nerve fibres, etc., etc. To all of which we make an afiirmative, choosing to disre- gard the writer's attempt at irony. We have learned in recent years that in individuals dying of long-standing nervous disease, the so-called functional as well as organic, there are almost invariably, especially if the indi- vidual be somewhat advanced in years, retrogressive changes in the nervous system. Although Mobius comes to the conclusion that in the majority of cases of Graves' Disease nothing characteristic or essential is to be found in the cervical sympathetic to explain the patho- genesis of the disease, St'does not seem to us that in- vestigation of the vegetative system of nerves in its peripheral and central distribution have been sufficiently comprehensive to give tenability to his position.