Some aspects of lymphadenoma (Hodgkin's Disease) / by H.D. Rolleston.

  • Humphry Rolleston
Date:
[1911?]
Catalogue details

Licence: In copyright

Credit: Some aspects of lymphadenoma (Hodgkin's Disease) / by H.D. Rolleston. Source: Wellcome Collection.

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    From “ The Practitioner ” for April, igiq Lmwji, hft>- - SOME ASPECTS OF LYMPHADENOMA (HODGKIN’S DISEASE). By H. D. ROLLESTON, M.D., F.R.C.P., Senior Physician, St. George's Hospital; Physician, Victoria Hospital for Children. History.—Although the condition was briefly described by Morgagni (1769), and in this country by Bright and Carswell, the credit of first drawing attention to it is usually given to Hodgkin—demonstrator of morbid anatomy at Guy’s Hospital —who, in 1832, contributed a paper “On some morbid ap¬ pearances of the absorbent glands and spleen/’1 It is probable that only a few of the seven cases given in his paper would now be regarded as lymphadenoma, and his account did not attract any attention and probably never would have done so had it not been for the loyal efforts of Sir Samuel Wilks2 who, in 1856, gave an account of “A peculiar enlargement of the lymphatic glands ” in a paper “ On cases of lardaceous disease and some allied affections.” He says that this affection is not lardaceous but is brought forward in connexion with that disease because it is either a variety of it or closely related to it. At the end of the paper there is an addendum saying that it was only after he had completed the article that he came on Hodgkin’s paper, and that had he been aware of its contents the statements about the originality of some of his own observations would not have appeared. Wilks3 finally, in 1865, made Hodgkin's name immortal by calling the disease after him. About this time (1864) Virchow described the large multinuclear or “lymphadenoma cells” which sub¬ sequent observers also noted, among them Langhans (1872), and Greenfield 4 in the course of a debate on the subject at the Pathological Society of London in 1878. General atten¬ tion, however, was not paid to this until Andrewes5 described fully the histological characters of the disease in another discussion at the same Society on “Lymphadenoma in its 1 Hodgkin, T. : Med.-Chir. Trans., Lond., 1832, XVII., 68. 2 Wilks : Guy’s Hosp. Rep., Lond., 1856, 3. ser., II., 131. 3 Wilks : Ibid., 1865, 3. ser., XI., 56. 4 Greenfield : Trans. Path. Soc., Lond., 1878, XXIX., 292 ; PI. XIII., Fig. 2. 5 Andrewes, F. W.: Ibid., 1902, LIII, 305. P 5733.—l. A