The pharmacological action and therapeutic uses of the nitrites and allied compounds : including the Croonian lectures for 1893 / by Daniel John Leech ; ed. by R.B. Wild.

  • Leech, Daniel John.
Date:
1902
Catalogue details

Licence: Public Domain Mark

Credit: The pharmacological action and therapeutic uses of the nitrites and allied compounds : including the Croonian lectures for 1893 / by Daniel John Leech ; ed. by R.B. Wild. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    well adapted for the administration of nitrite of ettyl, and from occasional examinations made of the strength of specimens in use, I can confirm Professor Dunstan's state- ment as to its stability. The large amount of alcohol which is required to administer such a dose as two minims of the nitrite seems to me its only drawback; but the combination of the nitrite and alcohol is in itself, I think, useful, and if alcohol be not desirable, a nitrite soluble in water may be given in place of the ethyl compound, since all nitrites have a similar influence. I believe, then, that the introduction of a fairly stable solution of ethyl nitrite is now called for, and that the time- honoured spiritus setheris nitrosi should disappear from the list of official remedies, since on account of its ready decom- position it is not adapted for administering the nitrite in definite doses. Should, however, there be any who find, or think they find, an advantage in the spirit, and both be included in the Pharmacop^eia_it^ems to me the present test of purity of the js^sSQ^t^^oiild di^ip^ For then the ethyl nitrite ^&«M haf3Iy^T)e con^dflired the cause of this advantage, ap^thijBjb^jn,g^ait-,^ouldlnot be necessary to ask that it shiujl^ contain a definite^'percentage of the nitrite. Certainl^S^ sweet~fl]Sfe ^ho;wld not be required to contain as much a^'''S-4a:3L4)er cent, of ethyl nitrite. I cannot help thinking that had it been easy to maintain so high a standard we should have heard of more evils arising from the popular use of this drug than we have done.
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