Endothelioma of the Gasserian ganglion : two successive resections of the ganglion, first, by the extradural (Hartley-Krause) operation, and secondly, by an intradural operation / clinical report by F.X. Dercum ; surgical report by W.W. Keen ; pathologic report by W.G. Spiller.

  • Francis Xavier Dercum
Date:
[1900]
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Licence: In copyright

Credit: Endothelioma of the Gasserian ganglion : two successive resections of the ganglion, first, by the extradural (Hartley-Krause) operation, and secondly, by an intradural operation / clinical report by F.X. Dercum ; surgical report by W.W. Keen ; pathologic report by W.G. Spiller. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    spinal ganglion, but in his study of ganglia removed from an executed man soon after death and hardened rapidly, he found that a pericellular space does not exist. Whether the cells lining the cell capsule are to be re- garded as endothelial or not seems undetermined. Their proliferation in an endothelioma might occur whether the cells resemble endothelium or epithelium. The great degeneration of nerve-fibers of the fifth nerve and the pressure caused by the tumor explain the intense pain felt by the patient, but it seems surprising that objective sensation in the face could have been so well preserved when the medullated fibers were so greatly degenerated. Axis-cylinders deprived of medullary sheaths may have existed, although such naked axis- cylinders are always difficult to detect. In two excellent papers on endothelioma that have recently appeared (Kelly,9 Sailer30), in which the litera- ture is carefully considered, no mention is made of mili- ary endothelioma, and Sailer says that endothelioma of the dura is almost invariably benign and rarely gives rise even to pressure symptoms. Dr. Kelly and Dr. Sailer inform me that in their study of the literature on endo- thelioma they have found no mention of the occurrence of numerous small endotheliomas. Our case of tumor of the Gasserian ganglion caused what may be regarded as numerous metastatic growths and—even more uncom- mon—miliary endotheliomas. I have also had a case of endothelioma of the cerebral dura in which pressure symptoms were very marked. BIBLIOGRAPHY. 1. Mitchell, John K.: Jour, of Nervous aud Mental Dis., June. 1898. 2. Hagelstem: Deutsche Zeitsch. f. Nervenheillcunde, vol. xiii, Nos. 3 and A p. 205. 3. Trenel: Bulletins et MOm. de la Soc. Anatomique de Paris. March, 1899, p. 326. i. Krause: Die Neuralgie des Trigeminus, p. 101. 5. Homen; Neurologisches Centralbl., 1890, p. 385. 6; Birch-Hirschfeld: Lehrbuch der Path. Anatomie. 7. Ziegler: Lehrbuch der Allgemeinen Pathologic. Ninth Edition. Vol. i. p. 431. . „ 8. v. LenhossiSk. Arch. f. Psychiatric, vol. xxtx, No. 2, p. 345. 9. Kelly: The Philadelphia Monthly Medical Journal,February. 1899. 10. Sailer: Contributions from the William Popper Laboratory of Clinicai Medicine. Reprinted prom Tint Journal op the American Medical Association April 28,1900
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