Dictionary of the active principles of plants: alkaloids : bitter principles; glucosides; their sources, nature, and chemical characteristics / with tabular summary, classification of reactions, and full botanical and general indexes. By Charles E. Sohn.
- Sohn, Charles E.
- Date:
- 1894
Licence: Public Domain Mark
Credit: Dictionary of the active principles of plants: alkaloids : bitter principles; glucosides; their sources, nature, and chemical characteristics / with tabular summary, classification of reactions, and full botanical and general indexes. By Charles E. Sohn. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
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![Colour tests (negative) : Concentrated sulphuric acid „ ,, ,, with sugar „ „ ,, „ nitric acid ^colourless. ., nitric acid hydrochloric acid (7a) ISOCINCHONIDINE A. ; prepared like Isoquinine ; crystalline plates ; M.P. '235°. Readily soluble in ether and chloroform. (7b) APOCINCHONIDINE A.; formed like Apoquinine, but no methyl group eliminated; crystalline, very bitter ; non-fluorescent. Precipitated by alkaline hydrates, and by ammonia, which gives an amorphous pp., becoming crystalline. No pp. Rochelle salt. (7c) CINCHAMIDINE A. (Hydrocinchonidine, Forst); accompanies Cin- chonidine, from which it maybe separated by fractional precipitation; C20H26N2O or C^H^NjO ; crystalline plates or needles ; M.P. 230°; loavo- rotitory ; not fluorescent. Soluble in alcohol and chloroform ; with difficulty in ether. (7/1) H0M0CIHCH0NIDINE A. [regarded by Skraup as merely impure Cinchonidine, see (7)] ; Ci9Ho2N.20 (Besse); accompanies Cinchonidine ; crystalline prisms or plates. Soluble in alcohol and chloroform, scarcely in water. (8) ARICINE A. (Manzini's Chinovatiue or Quinovatine ; Hesse's Cin- chonidine '?); exists to extent of 3 to 3£ per cent, in China de Cusco vera (false Calisaya bark), in which Moissan found no Quinine or Cinchoniue ; C._>:)H.,tiN,04-|-2H,0 (Gerhardt, Hesse, Moissan); isomeric with Brucine; crystallizes in long transparent needles; M.P. 188°; la3vo-rotatory (-f)K-18° in alcohol, — 92'30° in ether); alkaline, not bitter; salts mostly crystalline (but the sulphate gelatinous from water, though crys. from alcohol) ; acetate difficultly soluble in water. Soluble in 100 parts cold or 11 parts boiling alcohol, 33 parts ether; scarcely in water. Precipitants: Alkaline hydrates. carbonate^, i Ammonia, somewhat soluble in excess. [Not tartrates of soda or potash.] Tannic acid. Picric acid. Gold chloride, yellow amorphous. Phospho-tungstic acid) , -, , , • -naan T j 1 . • • j pp., cloud at 1 in .)0,000. Iodo-potassic acid | n > > Potassic iodide. Mercuric-potassic iodide, pp., cloud at 1 in 50,000. Colour tests (Wittstein believes the colours are due to impurity) : Concentrated sulphuric acid, dark green. „ nitric acid, intense green. Friihde's reagent, blue, changing to green. (9) CUSC0NINE A. (regarded by Wittstein as identical with preceding), C3H26N204 + 2EJ..0 ; crystalline plates or prisms, with metallic lustre; M.P. 110° (after loss of water) ; lasvo-rotatory ( - 54-3 in alcohol); feebly alkaline; not bitter ; not fluorescent; salts mostly amorphous ; sulphate gelatinous. Soluble in alcohol, acetone, and ether, very readily in chloroform, but scarcely in water. Precipitated by alkaline hydrates and ammonia ; scarcely soluble in excess. Other precipitants as under Aricine. Colour tests: Concentrated sulphuric acid, yellowish-green. Concentrated nitric acid colours the alkaloid dark green, the solution becoming yellowish-green. Friihde's solution, dark-blue ~ olive green warm blue on cooling. (9a) CUSC0NIDINE A. [possibly amorphous form of Cusconine (Hesse) ; coinpara also (8) and (9)] ; amorphous; dark brown. Reactions: Alkaline hydrates ) ,■ , ,, a , , . . J } dirty yellow Hocculent pp. Ammonia ) J J L1 Gold chloride \ yellow amorphous pp., soluble with difficulty in Platinum chloride \ in water. To the solution in concentrated acetic acid : Sulphuric acid gives no pp. (distinction from Paricine). Nitric acid, cloud, changing to pp. of Cusconidine nitrate. Hydrochloric acid, cloud, disappearing on addition of water. (9Z>) CUSCAMIDINE A.; closely resembles the above, the only difference (observed by O. Hesse, Ann. Chetn. Pharm., 200) being that Cuscamidine](https://iiif.wellcomecollection.org/image/b21503023_0047.jp2/full/800%2C/0/default.jpg)
