Dictionary of the active principles of plants: alkaloids : bitter principles; glucosides; their sources, nature, and chemical characteristics / with tabular summary, classification of reactions, and full botanical and general indexes. By Charles E. Sohn.
- Sohn, Charles E.
- Date:
- 1894
Licence: Public Domain Mark
Credit: Dictionary of the active principles of plants: alkaloids : bitter principles; glucosides; their sources, nature, and chemical characteristics / with tabular summary, classification of reactions, and full botanical and general indexes. By Charles E. Sohn. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
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![M.P 220°; dextro-rotatory ([a]j=+24-5°); neutral reaction; tasteless, odourless, poisonous (producing convulsions). Soluble in 70 parts water, 50 cold alcohol, in chloroform, benzene (and ether ?) ; scarcely in carbon bisulphide. Reactions: [Not precipitated by lead acetate, neutral or basic. ,, tannic acid. „ picric acid.] Fehling's solution, reduced. Phospho-molybdic acid, pp. Colour tests: Concentrated sulphuric acid, blackens. Concentrated nitric acid gives a crystalline nitro-derivative. On reduction with hydriodic acid, pouring off the liberated iodine and then adding potash, f uchsine red coloration. § 79. CORNUS Florida (Dogwood); Cornacece. Investigator : Geiger, Ann. Chem. Ph., 14, 206, etc. (a) CORNIN B. ; crys. silky needles ; neutral; bitter. Soluble in water, alcohol, ether. Precipitants: [Not lead acetate, neutral.] Lead acetate, basic. [Not tannic acid, „ ferric chloride.] Silver nitrate, white crys. pp. [Not mercuric chloride. ,, iodine solution. „ barium chloride.] (b) CORNUS RESINOID (Dogwood Quinine) ; neutral, tasteless, resinous. Soluble in ether and hot alcohol ; not in water. § 80. CORYDALIS group. Corydalis Dicentra cava Schwg., [C. bulbosa Pers. = G. tuberosa .Dec.=P>ulbocapnus cavus Bernh.], C. fabacea [=C. intermedia], and C. solida [Bulbocapnus digitatus = C. digitata = C. bulbosa Dec], (a); Fumaria officinale (Fumitory), (b), (? a), etc.; Fumariacecc. Aristolocia cava (Birthwort), (a) ; Aristolochice. [For A. Argentina, see separate entry.] Compare Berberis group, the alkaloids of which are probably chemically connected with these. See (c) below. (a) C0RYDALINE A. [Adermann's alkaloid No. 1, see (c); not Ader- mann's Corydaline, see (&) and (d)], Ci8H19N04 (Wicke) or C22H29N04 = [C18Hi7(CH30)4N] (Dobbie) ; crystallizes in prisms or needles; M.P. 134° (Dobbie) ; alkaline reaction; bitter in alcoholic solution, or in form of salts. Becomes yellow on exposure. 45 Soluble in ether, chloroform, benzene, amyl alcohol, carbon bisulphide, and turpentine; with difficulty in alcohol ; not in water, which precipi- tates it from alcohol. The best solvent is a mixture of ether and alcohol. Precipitants: Alkaline hydrates, sol. in excess (Wicke) ; insol. (M. Freund). Alkaline carbonates. Ammonia. [Not lead acetate, neutral or basic] Tannic acid (to alcoholic solutn). Picric acid, crystalline. Platinum chloride, yellow crys. Colour tests: Concentrated sulphuric acid, colourless ? (Dupuy says yellow to red). Nitric acid produces a brownish-red resinous substance. (b) FUMARINE A. [Adermann's Corydaline (?), Bulbocapnine (?), see(/)], C20H19NO2 (Reichwald) ; six-sided clino-rhombic prisms ; optically in- active, alkaline, bitter. Acetate very soluble. Soluble in alcohol (difficultly, Reichwald), in 11 parts chloroform, 78 benzene, in amyl alcohol and carbon bisulphide ; but with difficulty in water, and sparingly in ether or petroleum ether. Precipitated by Alkaline hydrates. [Not by lead acetate neutral.] Potassium bichromate, (pp. is F.Cr04] [No coloration or pp. with chlorine.] Colour tests: Concentrated sulphuric acid, dark violet, changing gradually to brownish-green. Concentrated sulphuric acid with potass, bichromate, brown (Reich- wald obtained a green with violet streaks). Nitre added to sulphuric acid solution, greens violet^yellow. Nitric acid, colourless cold, yellowish-brown on evaporation. Frohde's reagent, violet~vdark green. Seleno-sulphuric acid, pure violet. Vanadyl sulphate, emerald. Jfotass. suipnocyamde, white crys. Potass, chromate, yellow. „ bichromate. Sodium phospho-tungstate. Potass, iodide, white. Iodo-potassic iodide, brown. Mercuric - potassic iodide, yel- lowish-white.](https://iiif.wellcomecollection.org/image/b21503023_0057.jp2/full/800%2C/0/default.jpg)
