Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine ... / with an introduction, and copious notes, by the late Charles Thomas Haden ; translated from the French of the third edition of Magendie's "Formulaire."

  • François Magendie
Date:
1824
Catalogue details

Licence: Public Domain Mark

Credit: Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine ... / with an introduction, and copious notes, by the late Charles Thomas Haden ; translated from the French of the third edition of Magendie's "Formulaire.". Source: Wellcome Collection.

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    the solution digested with animal charcoal to deprive it of colour; it is next filtered and slowly evaporated, and the picrotoxine is ob¬ tained, on cooling, crystallized in quadrilateral, white, and transparent, prisms. Or, to the filtered decoction of these berries add acetate of lead whilst any precipitate falls. Filter and evaporate the liquid cautiously to the consistence of an extract. Dissolve in alcohol of 0.817, and evaporate the solution to dryness. By repeating the solutions and eva¬ porations, a substance is finally obtained equally soluble in water and alcohol. The colouring matter may be removed by agitating it with a little water. Crystals of pure picro¬ toxine now fall, which may be washed with a little alcoholb. PROPERTIES OF PICROTOXINE. Picrotoxine is inodorous, and of a very bitter taste ; it restores to blue, turnsol reddened by an acid ; it is sparingly, if at all, soluble in water, but very soluble in ether and alcohol, it combines with the greater part of the acids, forming salts, the taste of which is very bitter, and which are sparingly soluble in water. [Lies Dictionary of Chemistry, Art. Picrotoxiay anti Boullay, Annal, de Chimie, 80, 209.]
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