A treatise on diseases of the bones / By Thomas M. Markoe.
- Thomas M. Markoe
- Date:
- 1872
Licence: Public Domain Mark
Credit: A treatise on diseases of the bones / By Thomas M. Markoe. Source: Wellcome Collection.
Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.
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![dotted or f^ranular a]»])oar.ince of the surfaces on which they open. The further inicn)seoj(ieal chan«re5 in intianied bone are nierelv the more advanced statues of what has already been described; the bone-structure gradually disintegrates and dis- solves away, and this to an extent and in a manner which vary considerably, according to the characters of the inriani- niation and the tendency wliich it develops. Consequent, how- ever uj)on these merely destructive actions, we soon begin to see some attempts at reparation, and, in the moderate form of inflammation we are now studying, these actions soon assume the prominence. Into the natural cavities of the bone now enlarged by the ]>rocesses we have been studying, we soon have ])oured out the plastic exudations which are the results of the inflammation, and which begin to show organization. This organization leads by a strong and almost unvarying ten- dency to the development into bone, so that we soon begin to And new bone deposited in all the vacancies and porosities of the old. By means of these two processes, the first one of ab- sorption, and the second one of deposit, we have two conditions of bone produced, which are spoken of by writers as respectively rarefaction and condensation of bone. When in any given ease the absorbent actions are in excess, and more particles are removed than are replaced, then we may have an expan- sion with rarefaction of tissue, or, as it has been termed, osteo- porosis. When, on the other hand, the destruction is more than compensated by the deposit of new bone, then we have an expansion with consolidation of the inflamed bone, so that it becomes harder and heavier than natural. The enlargement of bone, with expansion or rarefaction of tissue, is the rarer of the two, though ^Nfr. Stanley says, I have learned that the simple swelling of bone, from expansion of its tissue, is one of the most frequent alterations to which it is liable. We have, in the cabinet of the New York Hospital, a specimen which shows this condition in a remarkable degree. It consists of the bones of tiie knee-joint taken from a ]>atient, a young adult, whose liml) was am])Utnted for long-continued disease of the joint. The whole bone is eidarged, without marked deformity, but every part has undergone a sort of atroj)hic change, by which the external lamina, the plates of the cancelli, indeed every](https://iiif.wellcomecollection.org/image/b21014413_0036.jp2/full/800%2C/0/default.jpg)
