Physiological and pathological researches / being a reprint of the principal scientific writings of the late T. R. Lewis ... Arranged and edited by Sir William Aitken ... G. E. Dobson ... and A. E. Brown.
- Timothy Richards Lewis
- Date:
- 1888
Licence: Public Domain Mark
Credit: Physiological and pathological researches / being a reprint of the principal scientific writings of the late T. R. Lewis ... Arranged and edited by Sir William Aitken ... G. E. Dobson ... and A. E. Brown. Source: Wellcome Collection.
Provider: This material has been provided by King’s College London. The original may be consulted at King’s College London.
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![I'ART I.] Corpuscles Imbedded in Ftoccidi of CJiolera Hvaciialions. Illustration II.:— Another case, the third liquid stool, presented a yellow colour, about one-sixth of which was composed of a whitish fiocculent sediment, in which the corpuscles were granular when the evacuation was voided, and exhibited araoiboid movements. The sediment presented precisely the same microscopical character as the second stage of the last described; a semi-membranaceous sul)stance, dotted with irregularly defined cells (Plate XIII, Fig. xliii), very like what is seen in exudations effused in catarrh. On very careful watching they are seen to protrude excessively delicate processes of an amoeboid character (Fig. xliv), just as the white blood-corpuscles do. Liquor potassce caused the membranaceous appearance to vanish after a time, reducing the cells to an aggregation of granular or molecular particles. Ether does not destroy them, nor does acetic acid, but it seemed to make manifest a delicate cell wall ; and iodine superadded enhanced this appearance, in many cases causing the contents to collect at one part of the cell (Fig. xlv). The membranaceous appearance had disappeared in the fluid on the fourth day, but the granular cells remained visible for nearly a week. Illustration III.;— The fifth evacuation of a patient suffering from the cold stage of cholera was examined half an hour after it was passed. It was colourless, with a few shreddy flocculi floating in it. It was slightly alkaline. The flakes presented the same membranaceous appearance as in the foregoing example (Fig. xliii), with numerous corpuscles, more or less intimately held in the meshes of this texture, a great number, however, being dispersed in the fluid; some were oil-like and some granular, examples of both kinds being spherical and oval, and the gradations from the merest particle of slimy or oily matter to the complete corpuscle were so fine, that it was impossible to point out any salient distinguishing character about them. When free, the hyaline and granular corpuscles were more or less round, but when contained in the meshes of this fibrillated texture, were generally elongated, as shown in the drawing (Plate XIV, Fig. xlvi). Iodine solution being added to the slide, it was observed that whereas some of them were coloured brownish-red, the greater portion became merely stained by the ordinary tint of the iodine (Fig. xlvii) ; all, however, in the course of the day becoming granular, but the distinction of brown-red and mere yellow remained. In the course of an hour other slides were prepared, but the microscopic appearance had become totally different. The oil-like bodies, of whatever shape, had become granular, and the field presented exactly the same appearance as presented in Plate XIII, Figs xli and xliii, while the addition of re-agents produced the same results. On the fourth day all traces of corpuscles had passed away, merely broken down molecular matter remaining. 4. Intermixed with the corpuscles already described are others to which I wish to allude with the greatest caution. Frequently a globule has been observed for some](https://iiif.wellcomecollection.org/image/b21296996_0057.jp2/full/800%2C/0/default.jpg)
