The chemical side of nervous activity. Croonian lectures no 1.
- Halliburton, W. D.
- Date:
- 1901
Licence: In copyright
Credit: The chemical side of nervous activity. Croonian lectures no 1. Source: Wellcome Collection.
Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)
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![with the degeneration, and continues high while absorption is occurring. It sinks to the normal when regeneration has set in. The following tabular summary gives our main results :— Cats' sciatic nerves Days after section Water Solids Percentage of phosphorus in solids Condition of blood Normal .. 1—3 .. 4—6 .. 65 1 64-5 69-3 34 *9 35-5 30-7 1*1 0-9 0-9 ( Minimal traces \ of choline pre- 1 cpn f: Choline more abundant 8 - .. 10 13 68-2 70- 7 71- 3 31-8 29-3 28-7 0-5 0-3 0-2 I Choline abun- j dant 25-27.. 29 72-1 72-5 27-9 27-5 traces o-o (Choline much ] less 44-60 .. 72-6 27-4 o-o Choline almost disappeared 100—106 66-2 33 8 0-9 Choline almost disappeared Condition of nerves [Nerves irritable | and histologi- ( cally healthy Irritability lost; degeneration beginning Dege neration well shown by Marchi reac- tion /Marchi reaction still seen, but absorption of degenerated fat has set in Absorption of fat practically complete Return of func- tion ; nerves regenerated We have paid some attention to the multiplication of the cells of the primitive sheath. This first becomes a marked phenome- non on the eighth day, and is possibly the result of irritation by the degenerated products. The phagocytic action of these cells at a later stage has been already mentioned. Later still, the cells become spindle-shaped and united end to end ; it appears to us that these cells are in their activity related nutritionally to the regeneration process. We have discussed the question whether or not they may take any part in the actual formation of the new axis cylinder, but at present we have insufficient evidence to show that they do so. Another question, which has not been alluded to in the fore- going pages, but which has inevitably been considered by us, is the mode of origin of the medullary sheath. The activity of the neurilemmal cells is a point in favour of the origin of the medul- lary sheath from them. On the other hand, the association of the complete return of function with the appearance of the](https://iiif.wellcomecollection.org/image/b2127180x_0126.jp2/full/800%2C/0/default.jpg)
