The elements of therapeutics : a clinical guide to the action of medicines / by C. Binz ; tr. from the 5th German ed., and ed., with additions, in conformity with the British and American pharmacopoeias, by Edward I. Sparks.
- Karl Binz
- Date:
- 1877
Licence: Public Domain Mark
Credit: The elements of therapeutics : a clinical guide to the action of medicines / by C. Binz ; tr. from the 5th German ed., and ed., with additions, in conformity with the British and American pharmacopoeias, by Edward I. Sparks. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
280/368 (page 268)
![that they excite severe irritation of the bowel. Digestion does not appear to be impaired by gamboge in ordinary doses, and in this as well as its other property it agrees with colocynth. Dose, gr. j.—v. Preparation:— Pilula CainbogicB Coinposita, U.S. (Gamboge, Barbadoes aloes, compound cinnamon powder, hard soap, syrup; about 1 in 6.) Dose, gr. v.—x. Oleum Crotonis, B.P., Oleum Tiglii, U.S. Croton Oil. Expressed from the seeds of Croton Tiglium (Euphorbiacese), a native of the East Indies. It is a fatty oil which contains Crotonic acid, and several volatile and non-volatile fatty acids (Buchheim). The acid is its active principle, and excites severe irritation when applied to the skin and the mucous membranes. It has not, however, been proved that the simple inunction of the oil into the abdo- minal waU can excite diarrhoea. InternaUy, a quarter of a minim will in the human subject cause watery diarrhoea. It is best administered in pills, or diluted with a fatty oil. The dose is from m^-J—^3.(!). Owing to its powerful action it should be prescribed with great caution. [Externally, it is apphed in a diluted form as a derivative liniment, and is used, but with very doubtful efficacy, in pulmonary affections. It generally produces a copious eruption of pustules, and a good deal of unpleasant irritation, and hence is unsuited to dehcate skins.] Preparation, B.P. :— Linimentum Crotonis. (Croton oil, 1 pt., oil of cajeput, rectified spirit, of each 3 J pts.) The composition of crotonic acid is as yet undetermined, but it appears to resemble that of ricinic acid. [Goa Powder, ChrysaroUn, also known as Araroha (not officinal), is imported from Bahia in South America. Its exact](https://iiif.wellcomecollection.org/image/b21042214_0280.jp2/full/800%2C/0/default.jpg)