Immunisation against infectious disease, 1990 / Department of Health, Welsh Office, Scottish Home and Health Department.

  • Great Britain. Department of Health
Date:
[1990]
Catalogue details

Licence: Open Government Licence

Credit: Immunisation against infectious disease, 1990 / Department of Health, Welsh Office, Scottish Home and Health Department. Source: Wellcome Collection.

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    given a prophylactic course of erythromycin. 5.3.5 HIV-positive individuals may be immunised against diphtheria in the 5.4 Use of the Schick test 5.4.1 The Schick test is recommended for individuals who may be exposed to diphtheria in the course of their work. In such cases immunity to diphtheria should be ensured by means of a Schick test carried out at least three months after immunisation is completed. 5.5 Schick test 5.5.1 An intradermal injection of 0.2m] of Schick test toxin is given into the flexor surface of the left forearm and 0.2m1 of Schick test control (inactivated toxin) material into the corresponding position of the right forearm, using separate syringes and needles. Readings should be made at 24-48 hours and five to seven days. Comparison of the appearances of the two injection sites will reveal responses attributable to immunity and to allergy. Four types of response may occur: a. Schick negative - No visible reaction on either arm. The subject is IMMUNE and need not be immunised or reinforced. b. Schick positive - An erythematous reaction develops at the site of the toxin injection, becoming evident in 24-48 hours and persisting for seven days or more before gradually fading. The control shows no reaction. The subject is NOT IMMUNE and requires to be immunised or reinforced. c. Negative-and-pseudo-reaction - Both injection sites show similar reactions after 48-72 hours, which fade within five to six days. The reactions are due to hypersensitivity to the components of the test materials. The subject is IMMUNE and need NOT be immunised or reinforced. d. Positive-and-pseudo-reaction - (also called combined reaction). Both injection sites show reactions after 48-72 hours but the reaction in the LEFT arm (toxin) is usually larger and more intense than that on the
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