On the animal alkaloids : the ptomaïnes, leucomaïnes, and extractives in their pathological relations / by Sir William Aitken.
- Date:
- 1889
Licence: Public Domain Mark
Credit: On the animal alkaloids : the ptomaïnes, leucomaïnes, and extractives in their pathological relations / by Sir William Aitken. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![a large quantity of molecular matter, -whicli does not dissolve in ether. The action of acetone on healthy- blood is found to be similar.*' The blood corpuscles break down into granular debris ; and such destructive effects of acetone on the blood accounts for such sym- I)toms as great dyspnoea and cyanosis; for the blood cells are so destroyed that they are no longer able to absorb and fix oxygen. In 1857 Fetters and Kaulich showed that acetone was developed in the blood of diabetics, as well as in chronic affections of the stomach and digestive organs, such as chronic gastric catarrh. The state of acetonaemia of various forms brings about great depression of the whole nervous system; and the source of the acetone is j)robably from the alcoholic and acetous fermentation of the grape sugar, and possibly of other organic matters in the stomach in catarrhal conditions.f Acetone has also been found in the blood and in the solid organs of patients dead of diabetic coma.]: It has been found in the urine ; and is often developed in the urine after it has been passed. § Yon Jaksch Penzoldt, and others, have shown that acetonuria is not peculiar to the diabetic condition but may occur in a variety of febrile states ; and that there are grounds for beheving that even the healthy organism may not be altogether free from acetone. It would appear from the researches of Baginsky, that amongst childi-en a physiological acetonuria of sHght degree and inconstant nature, does exist; that a pathological acetonuria is common * British Medical Journal for 1878, p. 79, Foster and Saundby. t Beohamp, Compt. Eendus, 1872. X Berti, London Medical Record, 1874. § Foster, loc. cit., and Kussmaul.](https://iiif.wellcomecollection.org/image/b21953181_0078.jp2/full/800%2C/0/default.jpg)
