On the study of the hand for indications of local and general disease / by Edward Blake.
- Blake, Edward T. (Edward Thomas), 1842-1905.
- Date:
- 1899
Licence: Public Domain Mark
Credit: On the study of the hand for indications of local and general disease / by Edward Blake. Source: Wellcome Collection.
27/198 (page 5)
![scurvy, rickets, gonorrhoea, syphilis, small-pox, scarlatina, septicaemia, malignant endocarditis, pyaemia, jaundice, cancer, typhus, measles, albuminuria and Hodgkin's disease. Many toxic agents have the power of producing petechias —for example, tincture of benzoin. (Tilbury Fox, Lancet, Feb. 7, 1874.) Amongst the commonest are quinine, copaiba, mercury, belladonna, arnica, phosphorus and ergot, but above all the iodides. Some of the petechial eruptions attributed to syphilis are undoubtedly due to iodide of potassium. Fournier, as early as 1877, described cases of purpura caused by iodide of potassium. To Jonathan Hutchinson is due the credit of drawing the attention of the profession to the perils of pushing iodides in certain persons. (See the Pedigree of Disease, p. 54.) Tom Robinson gave three grains of iodide of potassium every day to a man aged 63 : in six days a diffuse purpura appeared. (Lancet, March 4, 1893.) Stephen Mackenzie reports, in the same paper, the death of an infant of five months, with purpura, after a single dose of 2^ grains of iodide of potassium. A man took 45 grains of iodide of potassium for ten days. He showed on his hands, etc., erythema, urticarious weals and bullae [dermatitis herpetiformis]. (Mons. Danlos, Soc. M^dicale des Hopitaux, January, 1899.) Purpura followed by gangrene, has been recorded by Shepheard3 as occurring after the administration of sodium salicylate; such a condition might be mistaken for peliosis rheumatica [Schcenlein's disease]. Purpura accompanies many of the neuroses. It is seen with chorea and rheumatism, but more especially with the myelopathies, such as locomotor ataxia and its allies. The sites of lightning pains are particularly prone to be visited by purpura. According to Mr. Jonathan Hutchinson, the thrombotic form of purpura is often seen with varieosis. All this means that the various forms of neuritis, most](https://iiif.wellcomecollection.org/image/b20393908_0027.jp2/full/800%2C/0/default.jpg)