Bone sarcoma : an interpretation of the nomenclature used by the Committee on the Registry of Bone Sarcoma of the American College of Surgeons / by E.A. Codman.

  • Ernest Amory Codman
Date:
1925
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Licence: In copyright

Credit: Bone sarcoma : an interpretation of the nomenclature used by the Committee on the Registry of Bone Sarcoma of the American College of Surgeons / by E.A. Codman. Source: Wellcome Collection.

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    parts, librous, myxomatous, cartilaginous or bony, has probably very little mlluence in the prognosis, which apparently de¬ pends on the activity and quantity of the undifferentiated cellular portions ol these tumors. We have therefore abandoned the attempt to separate clinical entities according to the preponderance of any element. All forms have much the same natural history. Roentgenologically these tumors are far more frequently near the ends of the bone than in the shaft, although exceptions occur. I hey usually show a considerable amount of bone production, generally radiating outwards, but the more cellu¬ lar types may simply destroy bone and therefore show erosion and invasion roent¬ genologically, without producing the char¬ acteristic radiating spicules. Histologically these tumors usually show intercellular substance resembling librous tissue, bone, cartilage or osteoid as well as undillerentiated cellular tissue. Sometimes one or another ol these elements predomi¬ nates the picture, but usually all the elements may be found in some part of