Mandelix (elixir of ammomium mandelate B.D.H.) in the treatment of urinary infections / The British Drug Houses Ltd.
- British Drug Houses
- Date:
- [1936?]
Licence: Public Domain Mark
Credit: Mandelix (elixir of ammomium mandelate B.D.H.) in the treatment of urinary infections / The British Drug Houses Ltd. Source: Wellcome Collection.
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![, MANDELIX 5 indicated by a pH of 5-3, or lower. For the purpose of cattying out such tests there is available as part of the Mandelix Outfit a small testing equipment comprising a bottle of methyl red indicator, a test-tube marked at 2 c.c., a dropping-pipette, and a sealed tube containing a solution of methyl red buffered at pH 5:3 and forming a colour standard. The directions for carrying out the test ate as follows :— By means of a small, lipped, enamelled jug transfer a sufficiency of the urine to be tested to reach the 2 c.c. mark on the test-tube supplied with the outfit. Draw a quantity of the methy] red indicator from the bottle into the dropping-pipette supplied for the purpose and add five drops of indicator to the urine in the test-tube. Shake gently until the colour is uniform, then compare it with that of the liquid in the sealed colour-standard tube supplied. If a yellowish pink colour is produced, it is an indication that the urine is in- sufficiently acid, a condition which should be corrected by the administration of ammonium chloride. In practice, however, such administration is seldom necessary, the testing of the urine being simply a precautionary measure which may be dis- continued, or at least only done at intervals, after the first few days of treatment when it is reasonably certain that the urinary PH will remain at or below 5:3. Clinical trials with Mandelix have confirmed the truth of the hypothesis that by the administration of ammonium mandelate the pH of the urine is maintained at the necessary level in all but very exceptional cases, without the collateral administration of ammonium chloride. In the few cases, however, in which it is necessary to administer ammonium chloride in order to increase the acidity of the urine this can be done at the physician’s discretion either by giving one of the capsules supplied as part of the Mandelix outfit or by prescribing a mixture such as— R Ammon. chlorid. Grex Ext. glycyrrh. liq. m.x Aq. dest. ad Zi Moy tts cists In those rare cases in which the administration of Mandelix produces a urine which is excessively acid (with an accom- panying risk of casts being produced in the urine), that is to](https://iiif.wellcomecollection.org/image/b33459204_0005.jp2/full/800%2C/0/default.jpg)


