Clinical chemistry : an account of the analysis of blood, urine, morbid products, etc., with an explanation of some of the chemical changes that occur in the body, in disease / by Charles Henry Ralfe.
- Ralfe C. H. (Charles Henry), 1842-1896.
- Date:
- 1883
Licence: Public Domain Mark
Credit: Clinical chemistry : an account of the analysis of blood, urine, morbid products, etc., with an explanation of some of the chemical changes that occur in the body, in disease / by Charles Henry Ralfe. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![When one of these monatomic radicals of a dibasic acid replaces the hydrogen of ammonia, a monamide is formed. But, as there is still one atom of replaceable hydrogen attached to the radical, this atom can at any time be replaced by a metal or a hydrocarbon radical, and thus the acid character is not entirely lost. From a dibasic, the acid becomes, in fact, a monobasic one. Acids of this kind are called amic acids. Thus we have Oxamic acid. Silver oxamate. Methyl oxamate. c2o2 ho l c2o2 a3o ) ca CH3O ] H } N. H f N. H I N. hJ hJ hj (3) Glycollic and lactic acids are examples of acids which are diatomic as to their structure and monobasic as to their properties. Only one of the two typical hydrogen atoms that each contains can be replaced by metals. The difference has been indicated in the formula? given above for the acids by marking the replaceable hydrogen by a plus, and the non-replace- able by a minus, sign. The effect of this peculiarity is that two monad radicals, one neutral and one acid, can be derived from each acid. These radicals replace one atom of hydrogen in the single molecule of ammonia, just as the monad radicals of dibasic acids do, and monamides are formed ; but these mouamides are amic acids if the radical so introduced contain the replaceable atom of hydrogen, or neutral amides if it contain ouly the non-replaceable atom. Thus from glycollic acid we have Glycollamic Potassium Methyl acid. glycollatnate. glycoLLimate. C2H20 KO ) C2H20 CH30 ] H [• N h In hJ h](https://iiif.wellcomecollection.org/image/b21699513_0025.jp2/full/800%2C/0/default.jpg)
