The influence of intravenous injections of neo-salvarsan on the arterial blood pressure / by H.D. Rolleston.

  • Humphry Rolleston
Date:
[1915?]
Catalogue details

Licence: In copyright

Credit: The influence of intravenous injections of neo-salvarsan on the arterial blood pressure / by H.D. Rolleston. Source: Wellcome Collection.

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    pressure was 8 mm. Hg and the average fall in the systolic pressure 11 mm. Hg. In the other 9 cases the average rise in the diastolic pressure was 6 mm. and the average fall in the systolic pressure was 5.5 mm. Hg. By arranging these figures rather differently it is seen that seven hours after injection there is A fall in both the systolic and diastolic pres¬ sures in ... ... ... ... ... 55 A fall in the systolic pressure alone in... ... 18 Making a fall in the systolic pressure in 73 A fall in the diastolic alone in ... ... ... 7 Making a fall in the diastolic pressure in 62 A rise in both the systolic and diastolic pres¬ sures in ... ... ... ... ... 19 A rise in the systolic pressure alone in... ... 7 Making a rise in the systolic pressure in 26 A rise in the diastolic pressure alone in ... 18 Making a rise in the diastolic pressure in 37 The blood pressure seven hours after the intravenous injection of neo-salvarsan is therefore usually lower than the blood pressure before injection. In the systolic blood pressure there was a fall in 73 cases, as compared with a rise in 26, or, approximately, in the proportion of 3 to 1. The average fall in the systolic blood pressure was 14 mm. Hg. In the diastolic blood pressure there was a fall in 62 cases, as compared with a rise in 37, or in the proportion of 5 to 3. The average fall in the diastolic pressure was 9.6 mm. Hg. The fall in the diastolic pressure is therefore slightly less than in the systolic pressure. The fall of blood pressure seven hours after injection cannot be explained as due to fever, for a rise to 100° F. or more occurred in 30 cases only. Out of these 30 febrile cases the systolic pressure was lower in 25 and higher in 5 cases seven hours after injection than it was before injection. The average additional fall of the systolic blood pressure in the 25 cases was 4.5 mm. Hg, while the diastolic was lower in 17 and higher in 13 of the 30 febrile cases; and the average additional fall in the 17 cases was 2.6 mm. Hg. The influence of fever so far as it goes in depressing the blood pressure is even less marked on the diastolic than on the systolic blood pressure. Comparison of the Blood Pressure tahen Seven Hours after Intravenous Injection of Neo-salvarsan ivith the Average of the Blood Pressure Estimations on Sub¬ sequent Days. Out of 98 cases there were 58 in which the averages of both the systolic and diastolic pressures on the days sub¬ sequent to injection were lower than those seven hours after the injection. The average fall in the systolic pres¬ sure was 7.3 mm. Hg and in the diastolic pressure 10.4 mm. Hg. Among these 58 cases there were 17 with a temperature of 100° F. or more seven hours after in¬ jection, showing an average fall of 10 mm. Hg in the