A descriptive catalogue of the Pathological Museum of the London Hospital.

  • London Hospital Medical College. Pathological Museum.
Date:
[1890]
Catalogue details

Licence: Public Domain Mark

Credit: A descriptive catalogue of the Pathological Museum of the London Hospital. Source: Wellcome Collection.

    49/678 page 3
    HYPERTROPHY AND HYPERPLASIA. From a man aged 42, who was admitted in an unconscious state with spasmodic movements, chiefly of the left limbs, and died about two months afterwards. He had softening of the right optic thalamus, a fatty and scarred liver, atrophied testes, and empyema on the right side. James Bunt, Reg. no.1317. Admitted Nov. 11,1880. Autopsy, Feb. 11,1881. Dr. H. Jackson. 10. The left tibia and fibula, the former greatly enlarged at its upper part and containing an incompletely separated sequestrum in a smootli- walled cavity in the centre of the bone. The tibia has been divided longitudinally in a plane passing from side to side in front of the axis of the bone and exposing the sequestrum. It is seen that the enlarge- ment of the bone is due to the formation of cancellous tissue, which has filled up the medullary cavity. There is only a thin wall of compact bone at the surface, from which there are numerous osteo- phytic outgrowths. The lower end of the bone is also enlarged, and its medullary cavity is occupied by ingrowth of cancellous tissue. The sequestrum is composed of compact bone, much eroded. It is surrounded by a smooth-walled cavity, excepting at the upper end, where it is still adherent. From the lower end of the cavity there is a sinus, with a funnel-shaped opening on the inner surface of the bone. There is a backward bend in the bone a little above the middle.—The enlargement of this bone was the result of an irritative hypertrophy (chronic osteitis) doubtless of long duration, and refer- able possibly to the presence of the sequestrum in its centre. It is possible, however, that the sequestrum may have been of secondary occurrence, and resulted from necrosis of a mass of compact bone formed by sclerosing osteitis in the axis of the bone. The specimen was obtained by Mr. McCarthy from the body of a woman aged 67, who was admitted with concussion of the brain, from which she died shortly afterwards. The enlargement of the left leg attracted attention. There were no abnormal adhesions between the bone and the skin and subcutaneous tissue, and no scar on the former was observed. (See Trans. Path. Soc. vol. xxxv. p. 283.) 11. The lower end of the rectum with the anus, laid open and showing internal and external haemorrhoids. The former are elongated poly- poid projections of the mucous membrane of the intestine, the latter are similar but smaller projections of the mucous membrane at the verge of the anus. They consist of fibrous connective tissue con- taining dilated and varicose veins. 12. A portion of a greatly thickened cranium. It consists of the outer portion of the left parietal and contiguous parts of the frontal and occipital bones. The enlargement of the bone is due chiefly to great increase of the diploe. It is greatest towards the vertex, its section measuring about f inch at the thickest part. 13. A cluster of enlarged mesenteric glands with a coil of small intestine b 2
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