Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine, the hydrocyanic acid, narcotine, strychnine, nux vomica, emetine, atropine, picrotoxine, brucine, lupuline, &c. &c. / with an introduction and copious notes by the late Charles Thomas Haden, esq. ; translated from the French of the third edition of Magendil's 'Formulaire'.

  • Magendie, Francois, 1783-1855.
Date:
1824
Catalogue details

Licence: Public Domain Mark

Credit: Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine, the hydrocyanic acid, narcotine, strychnine, nux vomica, emetine, atropine, picrotoxine, brucine, lupuline, &c. &c. / with an introduction and copious notes by the late Charles Thomas Haden, esq. ; translated from the French of the third edition of Magendil's 'Formulaire'. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    a most beautiful violet-coloured precipitate is formed; this property appertains solely to bruciue b. ACTION OF BRUCINE ON THE ANIMAL ECONOMY. The action of brucine on the animal economy is similar to that produced by strychnine, but it is less energetic. Its intensity has appeared to us in some experiments to be to that of pure strychnine0 as 1 to 12. It required four grains (gr. 3.281 troy) of brucine to kill a rabbit. A tolerably strong dog, after having taken four grains experienced some strong attacks of tetanus, but recovered. Brucine might then be substituted for strychnine, and b Strychnine, extracted from the nux vomica, when treated by the same means, sometimes assumes a violet tint. Under such circumstances we may feel assured that it retains brucine; for the strychnine from St. lena- tius’s bean, and even that from the nux vomica, when per- fectly purified, does not produce the violet colour with the proto-hydrochlorate of tin.—M. c Dr. Andral, jun. has lately made some fresh compara- tive experiments on brucine and strychnine; and he has arrived at this result, that six grains of brucine are re- quired to produce the Effects of one grain of impure, and of a quarter of a grain of pure, strychnine. The difference of action would therefore appear to be greater than what we had at first estimated. M.— [Vide Strychnine.]