A textbook of human physiology / translated from [the] 6th German edition by W. Stirling.

  • Landois, Leonard
Date:
1888
Catalogue details

Licence: Public Domain Mark

Credit: A textbook of human physiology / translated from [the] 6th German edition by W. Stirling. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    arrest the locomotive movements, as well as tlie protrusion of pseudopodiu, althougli the leucocytes of ilillerent animals vary somewhat in their resistance to the action of drugs. <>uinine not only arrests the movcuients of the leucocytes when a]iiilied to them directly, but when injected into the circulation of a frog the leucocytes no longer pass through the walls oi the capillaries [lliii:). The chyle contains leucocytes, which are more resistant than thos'- of the blood, but less so than those of tiie coagulable transudations. The leucocytes of the lymphatic glands may also be dissolved {IIkkscJiciiImic/i). Relation to Aniline Pigments.—Ehrlich has ob-served a remarkable relation of the white corpuscles to acid (eosin, picric acid, aurantia), basic (dahlia, acetate of rosanilin), or neutral (picrate of rosanilin) reactions. The smallest jirotoplasmic graiudcs of the cells have difl'erent chemical atiiuities for these pigments. Thus Ehrlich distinguishes eosinophile, basophile, and neutro])hile granules witiiin the cells Eosinophile granules occur in the leucocytes which come from bone-marrow, the myelogenic leucocytes. The small leucocj'tes, i.e., those about the size of a coloured blood-cori)Uscle or slightly larger, are formed in the lymphatic glands, the Ij-niphogeiuc. The large aincuboid multi-nucleated cells, which are found outside the vessels in inflammations, exhibit a neutio],hile ii-action. Their origin is unknown, and .so is thiit of the large uni-nucleated cells, and the large cells with constricted nuclei. The eosinophile coi'puscles are considerably increased in leukicmia. The basophile granules occur also in connective-tissue corpuscles, especially in the neighbourhood of epithelium ; they are always greatly increased where chronic inflammation occurs. III. Blood-Plates.—Special attention lias recently been directed to a third element of the blood, the blood-plates or blood-tablets of Bizzozero ; pale, colourless, oval, round, or lenticular discs of variable size (mean, 3 /x ). lu a healthy man Fusari found 18,000 to 250,000 in 1 cubic millimetre of blood. These blood-plates may be recognised in the circulating blood of the mesentery of a 7 o 3 J) 5 ^ Fig. 1-2. •• Blood-]dates and their derivatives. 1, a red blood-cori)uscle on the flat; 2, on the side ; 3, unchanged blood-plafes ; 4, lymph-corpu.scle, surrounded by blood-jdates ; 5, altered blood- plates ; 6, lymph-coriirs de with two heaps of fu.sed blood-plates and threads of fibrin : 7, group of fused blood-].]ates ; 8, small group of partially dissolved blood-plates with fibrils of fibrin. cliloralised guinea-pig and the wing of the bat. They are precipitated in enormous iiutnber.s upon threads sus^enied in fresh shed blood. They may be obtained from blood flowing directly from a blood-vessel, on mixing it with 1 per cent, solution of osmic acid. They rapidly change in shed blood (fig. 12, 5), disintegrating, forming small [)articles, and ultimately dissolving. When several occur together they rapidly unite, form small groups (7), and collect into finely granular masses. Tliese masses may be associated in coagulated blood with fibrils of fibrin (fig. 12). [These blood-plates are best seen in the shed blood of the gninea-picr, especially if it be mi.xed vsith a .solution of sodic sulphate (sp. gr. 1022) or per cent. NaCl tinged with methyl- violet, liizzozero regards them as the agents which immediately induce coa<rulation and talu-
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