Progressive neuro-muscular Atrophy : (Peroneal Type of Charcot, Marie, and Tooth) : with report of three cases in a family without heredity / by Floyd F. Hatch, Boston.

  • Hatch, Floyd F.
Date:
1915
Catalogue details

Licence: In copyright

Credit: Progressive neuro-muscular Atrophy : (Peroneal Type of Charcot, Marie, and Tooth) : with report of three cases in a family without heredity / by Floyd F. Hatch, Boston. Source: Wellcome Collection.

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    PHY, (PERONEAL TYPE OF CHARCOT, MARIE AND TOOTH) : WITH REPORT OF THREE CASES IN A FAMILY WITH¬ OUT HEREDITY.*! By Floyd F. Hatch, Boston. [From the Medical Clinic of the Peter Bent Brigham Hospital, Boston, Mass.] The impulse given to the study of this type of muscular atrophy came in 1886 when Char¬ cot and Marie1, and Tooth2 coincidcntly in the same year published papers reviewing the myop¬ athies. Separately they established from clini¬ cal and pathological observations that the peron¬ eal form, beginning usually in early childhood and involving the extremities only, depended up¬ on neural as well as muscular degeneration and isolated it between the myopathic (muscular dystrophies) and the myelo-pathic (anterior poliomyelitis) affections. The characteristics of the affection as origin¬ ally described by Charcot and Marie are: 1. Progressive muscular atrophy beginning first in the feet and legs, not appearing in the hands and arms until several years later, the pro¬ gression of the atrophy being slow. 2. Relative in¬ tegrity of the muscles near the trunk, or at least much longer preservation of these than of the muscles of the distal ends of the limbs. 3. Integ¬ rity of muscles of the trunk, shoulders and face. * Reported at a medical meeting- at the Peter Bent Brigham Hospital, November 10, 1914. t Received for publication Dec. 22, 1914.