A modification of diphtheria antitoxin / by A.T. Glenny.

  • Glenny, A. T.
Date:
[1913?]
Catalogue details

Licence: Public Domain Mark

Credit: A modification of diphtheria antitoxin / by A.T. Glenny. Source: Wellcome Collection.

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    L+ mixtures, and it is hoped that one may be able to trace the gradual reduction of the “differential region” until the mixture with just enough serum to produce no local reaction is identical with the L+, and further modification until such a mixture becomes acutely lethal. TABLE II. Diphtheria antitoxic serum (Series E 148). Original value 440 units. Tests made at the end of 4J years at 37° C. Serum Toxin Local reaction 1/200 c.c. 1 test dose No record taken 1/100 1/75 ,, No swelling 1/50 ,, ,, Tests made at the end of 6§ years at 37° C. 1/100 c.c. 1 test dose No record taken 1/75 ,, ,, 1/50 ,, No swelling 1/40 1/30 Tests made at the end of 7 years at 37° C. >5 1/60 c.c. 1/50 1/45 1/40 1/35 1/35 1/30 1/30 1/25 1/25 1/20 1/10 1 test dose Very small swelling No swelling 5 > > > ) > »> ) * » ) Death 2 days 3 .. »> > > 7 20 2 2 3 3 13 2 2 n 3 7 9 16 17 „ 16 „ 23 „ 26 „ Survival 9 ) y y TABLE III. Diphtheria antitoxic serum (Series 469). Original value 470 units per c.c. Tests made at the end of 4| years at 37° C. Serum Toxin Local reaction Death 1/75 c.c. 1 test dose No swelling 3 days 1/50 y y yy 8 „ Tests made at the end of 6^ years at 37° C. 1/60 c.c. 1 test dose No swelling 3 days 1 /50 y y yy 7 ,, 1/40 > y yy 15 ,,
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