Thoughts on pulmonary consumption; with an appendix on the climate of Torquay / [William Herries Madden].

  • Madden, William Herries, -1883.
Date:
1849
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Licence: Public Domain Mark

Credit: Thoughts on pulmonary consumption; with an appendix on the climate of Torquay / [William Herries Madden]. Source: Wellcome Collection.

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    1 CHEMISTRY OF TUBERCLE. 9 pyiiij, phymatin^ and fat. These two last-mentioned analysts are the only ones who have detected the pre¬ sence of this peculiar animal substance phymatin. Scharlau gives as its constituents^ albumen, gelatin, fibrin, fat, and water. According to Boudet, incipient tubercles consist of albumen, casein, a substance analogous to fibrin, cere- bric acid, oleic and margaric acids, saponified fat, lactate of soda, and cholesterin. The ashes contain chloruret and sulphate of soda, phosphate and carbonate of lime, silica and oxide of iron. Cheesy tubercles are alkaline. When mixed with water, the solution is partly coagulable by heat. After removing the albumen the liquid gave, like milk, a precipitate with acetic acid, and when evaporated by a gentle heat, a pellicle was formed. The calcareous concretions contain 70 per cent, of the soluble salts, and only a small proportion of the insoluble.^ This last result is entirely at variance with the observations of other chemists, and if correct, would render their long persistence, in an organ abundantly supplied with fluids, a very inexplicable phenomenon. Simon^ gives the following analysis of tubercular matter from a horse : Water . . • 84-27 Fat containing cholesterin . . 1’40 Spirit extract with salts . 1’52 Caseous matter with water extract 1'14 Water extracts and salts . . 3-80 Insoluble constituents . .. 4-44 Bulletin de I’Acad. de Med-, quoted in the Med. Times of Nov. 2, 1844. 2 Animal Chemistry, translated by Dr. Day, Sydenham Soc. edit., vol. i, p. 478.
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