Internal secretion and the ductless glands / by Swale Vincent ; with a preface by E. A. Schäfer.

  • Swale Vincent
Date:
1912
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Licence: In copyright

Credit: Internal secretion and the ductless glands / by Swale Vincent ; with a preface by E. A. Schäfer. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    tissue, which is active in an opposite sense—-i.e., would tend to lower the blood-pressure [Osborne and Vincent (546, 547)]. In the case of the sympathetic ganglia this has actu- ally been found to be the case [Cleghorn (182)]. The author finds that glycerin and saline extracts of sympathetic ganglia produce a fall of blood-pressure, in spite of the presence in these ganglia of chromaphil cells like those in the medulla of the adrenal body.^ It appears, also, that it is impossible to obtain any rise of blood-pressure by injecting extracts of carotid glands into an animal, because there is so much admixture with various tissues whose extracts have a depressor effect [Vincent and Sheen (732, 733)]. (See, however, below, p. 175.) Poll and Summer (589) describe certain cells in the abdom- inal ganglia of Hirudo medicinalis which stain a yellowish- brown with Miiller's fluid. They consider it probable that these are homologous to the chromaphil cells discovered by Stilling (667, 668). Such cells were later described in a large number of leeches—Gnathobdellidae and Rhynchob- dellidse [Poll (587)]—and still later Poll gives a description and some very convincing drawings of these chromaphil cells in Nephthys scolopendroides. As regards the yellow cells of Pontobdella described by Leydig, these appear to be of a different nature. As pointed out by Poll, we are sadly in need of another micro-chemical test for adrenin-containing tissues. If the ferric-chloride reaction could be used for histological purposes, it would clear up many doubtful points. Roaf and Merenstein (612, 613) have expressed their belief that there is a substance in the hypobranchial gland of Purpura lapillus which is allied chemically and physiologi- cally to adrenalin. But the identity of the substance with adrenalin is denied by Dubois (225). Roaf has recently returned to the subject (611), and finds that in Purpura lapillus there are associated (1) a pressor substance in the strip of tissue adjacent to the so-called rectal gland ; (2) a purple-forming material in the same area; (3) a collection of bichromate-reacting granules also in the same situation. 1 Oleghorn did not ascertain that this result might be obtained from any nervous tissue, whether brain, spinal cord, or peripheral nerve [Osborne and Vincent (546, 547)] ; in fact, he states that this is not the case.
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