Internal secretion and the ductless glands / by Swale Vincent ; with a preface by E. A. Schäfer.

  • Swale Vincent
Date:
1912
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Licence: In copyright

Credit: Internal secretion and the ductless glands / by Swale Vincent ; with a preface by E. A. Schäfer. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    pressor substance can be extracted, not only from nervous tissues, but also from all kinds of muscular tissue, kidney, liver, spleen, testis, pancreas, ovary, and lung. They note, also, that other observers have extracted a depressor sub- stance from thyroid, thymus, adrenal, and pituitary body.^ Figs. 6, 7, and 8 show the effect of injection of extracts of muscle. Fig. 9 shows the effect of brain extract for the purpose of comparison. By this time it had become tolerably clear to the present writer that all animal tissues impart to watery or saline Fig. 6. — Dog. A.C.E., morphia. Injection of 5 c.c. protein extract of striped muscle (Vincent and Sheen). Fig. 7. — Dog. A.C.E., morphia curare, artificial respiration. Upper curve = limb; middle curve = in- testine; lower curve = carotid blood-pressure. Injection of an ether extract of striped muscle (Vincent and Sheen). extracts a substance or substances which, when injected into the circulation of a living animal, affect the arterial blood-pressure. The effect produced by these substances is depressor, with the exception of the medulla of the adrenal [ paraganglion suprarenale (Kohn)], other groups of chromaphil cells, and the infundibular portion of the pituitary body. It had also been rendered probable that these depressor effects of an extract are not to be regarded as an indication of an internal secretion on the part of the 1 Schafer (324) ; Svehla (361, 362) ; Moore and Purinton (255) ; Schafer and Vincent (328).
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