Clinical sketches illustrative of practical medicine and surgery / ed. by Noble Smith.
- Date:
- 1895
Licence: Public Domain Mark
Credit: Clinical sketches illustrative of practical medicine and surgery / ed. by Noble Smith. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![Dr. Rlien* reports liis observations on over fifty cases. Given in the declining stages of pertussis, it quickly checked the cough, improved the appetite, and stopped the vomiting. The course of the disease varied under this treatment from three to five weeks. The dose for infants under one year was gr. to gr. For children between three to five years gr. to h gr. There were no bad symptoms from its use. Antipyrin in large doses for chorea.'^—The conclusions deduced from Dr. T. McCall Anderson’s paper upon this subject are as follows :— 1. Antipyrin is not the dangerous drug which some observers have led us to suppose. 2. It may be given with safety in large doses, even in the case of children (as a rule), although the initial dose must be small, and slowly and cautiously increased, the patient being carefully supervised. 3. In large doses it often yields surprisingly good re- sults, and in chorea it is the only medicine from which cures may confidently be expected. Bad effects have probably arisen from— 1. Impurity of the drug, or, 2. Too large an initial dose, or, 3. Idiosyncrasy. Severe chorea in a boy aged 13.—On October 11, 1892, three doses of 5 grains were given without bad effect, and then the amount was rapidly increased. On October 13 he had 30 grains ; on the 15th 45 grains ; on the 17th GO grains, and so on, until November 14 he was taking 50 grains thrice daily. He was about a fortnight under treatment before the symptoms began to abate. From that time im- provement was continuous. He was well on November 25, when he left the Western Infirmary (Glasgow). He was to diminish the dose very gradually, and up to December 6 he remained perfectly well. Other cases are recorded, but there is no statement in the paper of the result after absolute cessation of the antipyrin. [Dr. McCall Anderson has since informed me by letter in answer to my inquiries as follows :— ‘ I have treated a good many cases ... in the same way and with the same success. The patients remained well for many weeks after cessation of the treatment, but I have not been able to follow them for any lengthened period of time. It is well to continue the treatment in decreasing doses for some weeks after all traces of chorea have disappeared.’—Ed.] Dangers of naphthol as an application to the skin — Baatz {Sem. Med. October 24, 1894) has seen acute nephritis follow friction with an ointment containing 2 per cent, of naphthol beta in two brothers, aged 6 and 8 re- ’ Miinch. med. Woch. Nov. 13, 1894. * British Medical Journal, December 1, 1894. spectively. The remedy was applied for scabies. This was cured, but three weeks afterwards albuminuria with oedema of the lower limbs came on. One of the boys died, and the diagnosis of nephritis was verified by fost-mortem exami- nation. In neither case had albuminuria previously existed, nor was there any history of an affection which could have been the starting-point of nephritis. The author therefore warns against the use of naphthol beta as a remedy for scabies, in spite of the powerful curative effect which it has on that disease.—Brit. Med. Jour. Dec. 29, 1894. PRESCRIPTIONS FOR ACNE VULGARIS 1. R, Naphthol Vaseline, Saponis viridis, aa Sulphur precip. M. et fiat pasta. 2. Camphor trit.. Vaseline, aa Pulv. cretin albae Saponis viridis Sulphur precip. M. et fiat pasta. 3. Resorcin, Amylis puri, aa Vaseline . Zinci oxidi M. et fiat pasta. 10 parts 20 parts 50 parts 10 parts 5 parts 15 parts 50 parts 5 parts 15 parts 5 parts These pastes can be applied until inflammation follows, or can be washed off in a quarter to half an hour, and can be followed by powders. The first two are best used in the latter manner, the third is milder for the mildest form of acne. Where single pustules are found, the following wash is used:— Acid. acet. cone., Tinct. benzoes, Spt. camphorie, aa . . .0 parts Spirit, q.s. ad 100 parts. M. Sig. Apply with sponge night and morning. (‘ The Therapeutic Gazette,’ Philadelphia.) flew Hpparatus By the editor THE TOE POST Boots to correct distortion of the great toe.—One of the most prevalent distortions to which civilised humanity is liable is Hallux Valgus—or, in other words, the bending](https://iiif.wellcomecollection.org/image/b2247383x_0037.jp2/full/800%2C/0/default.jpg)
