A case of chronic tuberculosis of the nose, tonsils, larynx, trachea, and main bronchi (sclerous lupus (?) without external manifestations), producing stenosis of the trachea and bronchi / by Thomas Whipham and Sheridan Delépine, read March 8, 1889.

  • Whipham, Thomas.
Date:
[1889]
Catalogue details

Licence: Public Domain Mark

Credit: A case of chronic tuberculosis of the nose, tonsils, larynx, trachea, and main bronchi (sclerous lupus (?) without external manifestations), producing stenosis of the trachea and bronchi / by Thomas Whipham and Sheridan Delépine, read March 8, 1889. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    Ln£ehZ7r ' 1681011 aS °ot y-'ifiel thatithas' 8. The same answer can be given with reo-arrl in +t,q usual seat of the lesion. The ca£ of E^nslyt n that respect, for it shows that, in some cases at leasfnatho ogists may have been in doubt regarding the nature ofcet tarn lesions which may have been recorded as syphilid because there was no distinct evidence that they were^f other orTg 4. As to the changes observed in the epithelium thev drvness^rtf ^ ^ ?m> ^ -1 i-itSn dryness of the membrane, due to destruction of the mucous glands. A similar stratification of the epithelium is observed m certain acute inflammations of the air-passages, but in those cases, the proliferation of the epithelium taking place rapfdl? the cells hare no time to undergo the changes leading to the formation of definite squamous and spinous cells. On the other hand, it is well known that mucous membranes exposed to the direct drying influence of the external air often become covered with stratified squamous epithelium. Given any process that will lead to irritation of the epithelium and drying of its surface, or possibly the latter only, we may ex- pect as a result the formation of a stratified squamous epithe- lium. We may therefore safely assume that the state of the epithelium has nothing specific in this case, and is the simple result of the changes which have taken place in the subjacent strata. Hence it is reasonable to discard entirely this objec- tion On the other hand, it is well known that great hyper- trophy of the rete Malpighii is not an unknown feature in tubercular lupus of the skin. 5. The excessive formation of cicatricial tissue in the trachea can hardly be said to be a serious objection; the for- mation of fibrous tissue is one of the commonest results of chronic tuberculosis, and that this formation has not been before observed in the trachea to the same extent as in the present case is no insuperable objection. Then we are accus- tomed to consider at least some forms of lupus as distinctly
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