Non-specific immunity.

London : University of London Audio-Visual Centre, 1973.

1 encoded moving image (54.09 min.) : sound, black and white.

00:54:09

University of London

Unrestricted

CC-BY-NC

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

In English

Presented by Dr John Humphrey, National Institute for Medical Research, London. Introduced by Dr Ian Gilliland. Produced by Peter Bowen. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.

Segment 1 Gilliland introduces Humphries. Humphries describes why he is interested in non-specific immunity as opposed to more specific kinds of immunity. Time start: 00:00:00:00 Time end: 00:05:39:00 Length: 00:05:39:00

Segment 2 Humphries talks about how microbes can be prevented from penetrating the body without this process involving specific immunological mechanisms. Time start: 00:05:39:00 Time end: 00:11:14:00 Length: 00:05:35:00

Segment 3 Humphries discusses antibodies, differentiating between those inherited at birth from the mother and those acquired during life. Time start: 00:11:14:00 Time end: 00:15:02:12 Length: 00:03:48:12

Segment 4 Humphries continues to look at antibodies and he introduces a short film sequence showing human granulocytes ingesting bacteria. Time start: 00:15:02:12 Time end: 00:19:51:20 Length: 00:04:49:08

Segment 5 Humphrey explains, in depth, the role of granulocytes in the human immune system. Time start: 00:19:51:20 Time end: 00:24:59:00 Length: 00:05:07:05

Segment 6 Humphrey continues his discussion and detailed description of granulocytes and the role they play in the immune system. He then moves on to discuss cytotaxins. Time start: 00:24:59:00 Time end: 00:29:14:20 Length: 00:05:45:20

Segment 7 Humphrey describes which kind of enzymes are most prevalent in granulocytes - these are listed in a table. He also refers to electron micrographs of macrophages. Time start: 00:29:14:20 Time end: 00:37:16:00 Length: 00:08:02:00

Segment 8 Humphrey talks about opsonins which are specific antibodies which have a specific function during an immune response. Time start: 00:37:16:00 Time end: 00:41:04:00 Length: 00:03:48:00

Segment 9 Humphrey moves on to discuss adjuvants which increase the presence of macrophages during an immune response. Time start: 00:41:04:00 Time end: 00:49:13:00 Length: 00:08:09:00

Segment10 Humphrey concludes the lecture and summarises the main points. Time start: 00:49:13:00 Time end: 00:54:09:13 Length: 00:04:56:13