Food Additives and Contaminants Committee report on the review of sweeteners in food.

  • Great Britain. Food Additives and Contaminants Committee
Date:
1982
Catalogue details

Licence: Open Government Licence

Credit: Food Additives and Contaminants Committee report on the review of sweeteners in food. Source: Wellcome Collection.

    46/70 (page 40)
    81. Coulston F etal(1975). Long-term administration of artificial sweeteners to the Rhesus monkey (M. mulatta). Fd Cosmet Toxicol 13, 297—299. 82. Coulston F et al (1978). Long-term safety evaluation and metabolism of o—benzoic sulphimide (saccharin) in Rhesus monkeys. Ecotoxicol Environ Safety 2, 33—48. 83. Das A (1979). Mutagenic effects of saccharin on Aspergillus niger. J Gen Microbiol 1/4, 221—222. 84. Ershoff B H and Bajwa G S (1974). Inhibitory effect of sodium cycla- mate and sodium saccharin on tumour induction by 2—acetylaminofluorene in rats. Proc Soc Exp Biol Med 145, 1293—1297. 85. Fitzhugh O G et al (1951). A comparison of the chronic toxicities of synthetic sweetening agents, J Am Pharm Ass 45, 583—586. 86. Food Chemical News 2] (13), 37. (11 June 1979). House unit votes saccharin moratorium extension to June 30, 1981. 87. Fukushima S and Cohen S M (1980). Saccharin-induced hyperplasia of the rat urinary bladder. Cancer Res 40, 734—736. 88. Green U et al (1980). Syncarcinogenic action of saccharin and sodium cyclamate in the induction of bladder tumours in MNU-pretreated rats. Fd Cosmet Toxicol 18, 575—579. 89. Hayes W (1980). A study of the kidney and bladder of rats fed various doses of saccharin. In “Proceedings of the Saccharin Working Group of the Toxicology Forum” held 27 July 1980 at the Given Institute of Pathobiology. 90. Herbold B A and Lorke D (1980). On the mutagenicity of artificial sweeteners and their main impurities. Mut Res 74, 209. 91. Hicks R M et al (1975). Evaluation of a new model to detect bladder carcinogens or co-carcinogens: results obtained with saccharin, cyclamate and cyclophosphamide. Chem—Biol Interactions J], 225—233. 92. Homburger F (1978). Negative lifetime carcinogen studies in rats and mice fed 50,000ppm saccharin. In “Chemical Toxicology of Food” edited by Galli, C Let al, Elsevier. Also unpublished report of Bio-Research Consul- tants Inc. Massachusetts, USA, contract NIH-NCI—E—68—1311, May 1973. 93. Hoosen J et al (1980). Orthotoluene sulphonamide and saccharin in the promotion of bladder cancer in the rat. Br J Cancer 42, 129-147.