Experiments to ascertain if the domestic fowl of Uganda may act as a reservoir of the virus of sleeping sickness (Trypanosoma gambiense) / by Sir David Bruce, A.E. Hamerton and H.R. Bateman.

  • David Bruce
Date:
[1911?]
Catalogue details

Licence: Public Domain Mark

Credit: Experiments to ascertain if the domestic fowl of Uganda may act as a reservoir of the virus of sleeping sickness (Trypanosoma gambiense) / by Sir David Bruce, A.E. Hamerton and H.R. Bateman. Source: Wellcome Collection.

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    The 13 experiments carried out on these lines are now given in tabular form, in Table I below :— Table L. | No No. of pie No. of No. of infected flies of expert- flies used. | fowl fed on. | found during Result. Remarks. ne: experiment. 19154 250 Expt. 1926 i Negative | Proved infective flies fed on this fowl. 19156 100 » 2059 1 7% | Proved infective flies fed on this fowl. LOL 50 see PB NEY — rs Doubtful whether infected flies fed on this fowl. 1918 100 » 1927 — . Proved infective flies fed | on this fowl. | 2081 120 5 2074 2 rs Proved infective flies fed on this fowl. 2082 100 » 2087 12 i Proved infective flies fed on this fowl. 2208 100 oe eee) 0 Ps Proved infective flies fed | on fowl, but no flies dissected. 2325 160 5 2004 2 4 Proved infective flies fed | on fowl. 2362 110 ,eraeGs 7 | z Proved infective flies fed on fowl. : 2365 300 Se oaG 0 7. Flies not dissected, but were proved infective. 2366 150 5» 2364 0 bg | Flies not dissected, but . were proved infective. 2390 180 FeO, 7 - Proved infective flies fed on fowl. 2395 100 5 2096 1 Hs Proved infective flies fed on fowl. Remarks.—In these experiments it is seen that 1820 laboratory-bred and laboratory-infected Glossina palpalis were fed on 13 fowls, with uniformly negative results. With one exception, Experiment 1915 ¢, the flies were proved to be infective by feeding them on animals susceptible to Trypanosoma gambiense infection. That the fowls had not become infected with Trypanosoma gambiense was proved by carrying out the three tests given above, under headings a, 6, and e. In Experiment 2325, the liver, spleen and bone-marrow of Fowl 2384 were also examined for trypanosomes, and 10 c.c. of the pooled pulp injected into a normal monkey. This monkey remained healthy. A further series of experiments bearing on this question was carried out. These experiments are not so complete. The procedure was as follows :— A varying number of laboratory-bred Glossina palpalis were fed for several days on Z'rypanosoma gambrense-infected antelope. The infected flies were then fed for varying periods on fowls. The fowls were then killed and 2 cc. of their blood were injected into a normal monkey. The monkey’s blood was examined for 7’rypanosoma gambiense bi-weekly for a month after the injection of the fowl’s blood. The experiments are given in tabular form.
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