Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'.

  • François Magendie
Date:
1823
Catalogue details

Licence: Public Domain Mark

Credit: Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'. Source: Wellcome Collection.

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    CHEMICAL PROPERTIES OF QUININE. Quinine is white and incrystallizable ; it is as little soluble in water as the cinchonine ; it is much more bitter, however, to the taste. Its salts also are in general more bitter ; they are distinguished by a pearly aspect. Quinine is very soluble in ether, while cinchonine is very little so. This difference not only serves to distinguish these cases, but also to separate them when united. PREPARATION OF SULPHATE OF QUININE. M. Henry the younger has lately made known an expeditious and cheap process for directly obtaining the sulphate of quinine. He digests, repeatedly, in hot water, acidulated by sulphuric acid (6 or 8 grammes [gr.92.66 or gr. 123.55 T.] to each kilogramme [oz. 32.17 T.] of distilled water). He blanches the liquors by means of hot lime, and washes the precipi¬ tate to separate the excess of lime. He repeatedly digests this precipitate, when well drained, in alcohol at 36° (.837). He then obtains, by distillation, a brown viscid matter, which becomes brittle when cold, and is very
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