Physiological principles in treatment / by W. Langdon-Brown.

  • Walter Langdon-Brown
Date:
1914
Catalogue details

Licence: Public Domain Mark

Credit: Physiological principles in treatment / by W. Langdon-Brown. Source: Wellcome Collection.

    270/426 page 258
    4. Products of putrefaction—e.g., indol. 5. Products of abnormal pathogenic bacteria present in the intestine. The first two do not concern us here. The reaction of the body against them differs in important respects from the method adopted against bacterial poisons. The neutralizing substances are normally present in the body, and are not specific, each of them combining with several poisons. Fromm points out that these reactions are few and simple, such as oxidation, reduc¬ tion, hydration, dehydration, and methylation. The protective substances are also few, such as proteins, bile acids, glycuronic acid, etc. They are not the re¬ sult of any special adaptation to meet a pathological condition. They are there as the result of normal metabolism; they have an affinity for various chemical substances, some of which happen to be poisons. If these enter the body, they are neutralized to some extent, though, as a rule, very incompletely. This is a very different reaction from the formation of highly specific immune substances against bacteria and their products. Intoxication by Intermediate Products oi Digestion. Peptone is not the end-product of digestion, but the process is carried further to simpler amine bodies. As intravenous injections of proteoses and peptones will cause symptoms, it has been suggested that intestinal intoxications may result from absorption of these inter-
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