Handbook of materia medica, pharmacy and therapeutics : including the physiological action of drugs, the special therapeutics of disease, official and extemporaneous pharmacy, and minute directions for prescription writing / by Sam'l O.L. Potter.

  • Samuel Otway Lewis Potter
Date:
1887
Catalogue details

Licence: Public Domain Mark

Credit: Handbook of materia medica, pharmacy and therapeutics : including the physiological action of drugs, the special therapeutics of disease, official and extemporaneous pharmacy, and minute directions for prescription writing / by Sam'l O.L. Potter. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

    114/860 page 104
    Syrupus Ferri Bromidi, Syrup of Bromide of Iron,—is a syrupy liquid containing lo per cent, of Ferrous Bromide, FeBrj, prepared by acting on Iron Wire 35 parts with Bromine 75, adding Sugar 600 and Water up to looo parts. A translucent, pale-green, odorless liquid of sweet, ferruginous taste and neu- tral reaction. Dose, jss-j. [Hydrobromic Acid is described on page 26, Ethyl Bromide on page 43, and Camphora Monobromata under Camphora.] Physiological Action. Bromine is an active and very painful escharotic, a deodorant and an antiseptic, setting free ozone. Its vapor is highly irritant to the respiratory mucous membrane and the eyes, producing cough, hoarseness and dyspnoea. Internally, it is an active, cor- rosive poison, causing violent gastritis, depression and collapse. The Bromides are cerebral and spinal depressants, alteratives, antispasmodics and hypnotics. They have a disagreeable, saline taste, and are very diffusible, but slowly eliminated. They are decomposed in the blood, and reformed at the points of elimina- tion (fauces, bronchi, intestines, skin and kidneys), where they irritate the mucous membranes. Continued for some time, they produce severe gastric catarrh. They reduce the number of the respirations and the heart's action and force, and, though dimin- ishing the calibre of the arterioles, they lower arterial tension. They produce somnolence by lessening the activity of the brain- cells,—diminish the sensibility of the peripheral nerves, causing anaesthesia of the skin and mucous membranes,—impair motility and the sexual function. They also cause pallor, emaciation, lowered body-temperature, acne on the face and upper extremi- ties, fetid breath, dysphagia, sluggish reflexes, defective coordi- nation, and, if long-continued, may even impair the mental fac- ulties, producing melancholia with suicidal tendency and periph- eral paralysis extending to the centres. The general result of their action is termed Bromism, and this condition is heralded by the acne and lowered faucial sensibility. It is probably due to the sedative influence of these agents on the sympathetic ner- vous system, causing a general anaemia of the brain, spinal cord, sexual organs and skin. Potassium Bromide is the most paralyzant to the heart and muscles, and is the least hypnotic. It contains less bromine than the others, 66 per cent. Sodium Bromide is the least toxic, but the most hypnotic, and is most energetic in its action on the circulation. It contains 78 per cent, of bromine. Ammonium Bromide resembles the potassium salt in action,
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