Some clinical aspects of pernicious anaemia / by Herbert French.

  • French, Herbert Stanley, 1875-1951.
Date:
1909
Catalogue details

Licence: In copyright

Credit: Some clinical aspects of pernicious anaemia / by Herbert French. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    1891, and notwithstanding his “lumbago” remained well enough to work on and oft' for over four years before repetition of his old weakness and pallor compelled him to seek hospital treatment again. He was in from February 7th, 1896, till JMarch 9th, 1896. He presented the typical pale yellow colour. His tissues were flabby, but not wasted. The urine sometimes exhibited a marked urobilin band sjjectroscopically, sometimes none. The temperature was typically up to 100° F. every night, and not below 98° F. in the morning as a rule. The nervous reflexes were natural. Arsenical treatment was adopted, and some relief ensued. The patient was discharged, able to walk about, but unable to do labourer’s work. He slowly relapsed, and was re-admitted on March 1st, 1897. He seemed to get progressively worse, and yet he lived for two years after his discharge on May 20th, 1897. Mrs. E. writes on August 15th, 1907: “ Mr. E. died two years after leaving Guy’s Idospital, suft'ering from jDrostration and great pains in his head, it was indeed sad to see such suffering, and the brain very much affected.” During his last stay in hospital his temperature was again typically between 99° F. and 100° F. each night. The spleen, formerly not felt, now came 2 inches below the ribs, and the liver came 1 inch below the costal margin in the right nipple line. Ophthalmoscopic examination revealed neither optic neuritis nor retinal hsemorrhages. The blood counts were as follows :— Date. Ecd corpuscles per cub. mm. Ecd corpuscles per cent, of normal. Hffiiiioglobin per cent, of normal. Colour index. 1890. February ... 2,400,000 48 53 1 -104 March 2,400,000 48 55 1 -148 1891. September 18 1,400,000 28 28 1 -000 „ 25 1,100,000 22 25 1 -136 October 5... 1,800,000 36 35 0-972 „ 19 2,100,000 42 35 0 -833 ,, 20 1,800,000 36 36 1 -000 „ 29 1,800,000 36 40 1-111 „ 31 2,000,000 2,900,000 40 40 1 -000 November 2 58 50 0-862 „ 9 3,350,000 67 60 0-895