The abnormal behaviour of glyoxaline-carboxlic esters and anilides towards diazonium salts / by Robert George Fargher and Frank Lee Pyman.

  • Fargher, Robert George.
Date:
1919.]
Catalogue details

Licence: Public Domain Mark

Credit: The abnormal behaviour of glyoxaline-carboxlic esters and anilides towards diazonium salts / by Robert George Fargher and Frank Lee Pyman. Source: Wellcome Collection.

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    Ethyl $-GlyoxalineA-'pro'pionate.—This was purified by crystal¬ lisation of the hydrogen oxalate from alcohol. The ester formed an oil, which gave an immediate blood-red colour with sodium diazobenzene-p'-sulphonate in aqueous sodium carbonate. The hydrogen oxalate separates from alcohol in colourless, shimmering leaflets, which are anhydrous and melt at 160° (corr.) after sintering from 155°. It is readily soluble in water or hot alcohol, but sparingly so in cold alcohol. Found: C = 48T; H = 6*0; N = 11'8. (C8H1202N2)4(C2H204)3 (9427) requires C-48'4; H = 5'8; N = ll*9 per cent. Ethyl a-hydroxy-fi-glyoxaline-i.-'pro'pionate crystallises from dry chloroform in minute, colourless plates which melt at 118—119° (corr.), and are anhydrous. It is readily soluble in water or alcohol, sparingly so in chloroform, and insoluble in ether. It gives a cherry-red colour with sodium diazobenzene-^p-sulphonate in aqueous sodium carbonate. Found: C = 52‘3; H = 6*5. C8H1203N2 (184*1) requires C = 52*2; H = 6*6 per cent. Wellcome Chemical Research Laboratories, London, E.C. 1. [Received, July 12th, 1919.] PRINTED IN GREAT BRITAIN BY R. CLAY AND SONS, LTD., BURNS WICK STREET, STAMFORD STREET, S.E. 1, AND BUNGAY, SUFFOLK.