Some colour reactions of adrenine and allied bases / by A.J. Ewins.

  • Ewins, Arthur James.
Date:
1910
Catalogue details

Licence: Attribution 4.0 International (CC BY 4.0)

Credit: Some colour reactions of adrenine and allied bases / by A.J. Ewins. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    SOME COLOUR REACTIONS OF ADRENINE AND ALLIED BASES. By A. J. EWINS. {From the Wellcome Physiological Research Laboratories, London.) The physiological investigation of a number of bases very closely related to adrenine in chemical constitution has recently been carried out in these laboratories. In view of this relationship it was considered of interest to examine these bases with regard to the more characteristic colour reactions which from time to time have been suggested for the identification or estimation of adrenine in various fluids. Apart from those reactions of the latter base which are due to the fact that it is a catechol derivative, the following characteristic reactions have been described. (1) The production of a rose red colour on the addition of iodine (Yulpian)1. (2) The formation of a red colour on addition of mercuric chloride (Comessatti)2. (3) The production of a reddish violet colour by the action of potassium biiodate and phosphoric acid (Frankel and Allers)3or by the action of iodic acid (Krauss)4. The reaction with iodine. The fact that a substance was present in the supra-renal gland which gave a rose red colour with iodine was first observed by Yulpian {loc. cit.). Later when the isolation of the physiologically active principle of the supra-renal gland had shown that this compound was the chromo- genic substance observed by Vulpian this reaction was suggested by 1 Vulpian. Compt. Rend. 1856. xliii. 663. 2 Comessatti. Munch, med. Wochenschr. 1908. No. 37. 3 Frankel and Allers. Biocliem. Ztschr. xvnt. 40. 1909
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